Gene Symbol | CLVS2 |
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Entrez Gene | 134829 |
Alt Symbol | C6orf212, C6orf213, RLBP1L2, bA160A10.4 |
Species | Human |
Gene Type | protein-coding |
Description | clavesin 2 |
Other Description | clavesin-2|retinaldehyde binding protein 1-like 2 |
Swissprots | Q5SYC0 B4DHL0 Q5SYC1 B3KTG5 C8UZT4 |
Accessions | EAW48160 EAW48161 EAW48162 Q5SYC1 AK055705 AK095527 BAG53077 AK295158 BAG58172 BC101376 AAI01377 BC101377 AAI01378 BK006900 DAA06537 BM684470 NM_001010852 NP_001010852 |
Function | Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). {ECO:0000250, ECO:0000269|PubMed:19651769}. |
Subcellular Location | Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250}. Early endosome membrane {ECO:0000269|PubMed:19651769}; Peripheral membrane protein {ECO:0000269|PubMed:19651769}. |
RLBP1L2 CRISPR/Cas9 KO Plasmid (h) - sc-414417 from Santa Cruz Biotechnology
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RLBP1L2 HDR Plasmid (h) - sc-414417-HDR from Santa Cruz Biotechnology
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RLBP1L2 Double Nickase Plasmid (h) - sc-414417-NIC from Santa Cruz Biotechnology
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RLBP1L2 Double Nickase Plasmid (h2) - sc-414417-NIC-2 from Santa Cruz Biotechnology
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RLBP1L2 CRISPR Activation Plasmid (h) - sc-414417-ACT from Santa Cruz Biotechnology
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RLBP1L2 CRISPR Activation Plasmid (h2) - sc-414417-ACT-2 from Santa Cruz Biotechnology
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RLBP1L2 Lentiviral Activation Particles (h) - sc-414417-LAC from Santa Cruz Biotechnology
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RLBP1L2 Lentiviral Activation Particles (h2) - sc-414417-LAC-2 from Santa Cruz Biotechnology
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RLBP1L2 siRNA (h) - sc-95286 from Santa Cruz Biotechnology
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RLBP1L2 shRNA Plasmid (h) - sc-95286-SH from Santa Cruz Biotechnology
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RLBP1L2 shRNA (h) Lentiviral Particles - sc-95286-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU011471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6277 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6277 from Sigma-Aldrich
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CLVS2 siRNA (Human) - CRJ5154 from Cohesion Biosciences
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CLVS2 - MBS8207411 from MyBioSource
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shRNA set against Human CLVS2 (NM_001010852.2) - SHH265817 from Creative biogene
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Human CLVS2 siRNA - orb275655 from Biorbyt
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CLVS2 shRNA Plasmid (Human) - CHJ5154 from Cohesion Biosciences
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CLVS2 miRNA 3'UTR clone - MiUTR1H-01466 from Creative biogene
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