| Gene Symbol |
CNOT10
|
| Entrez Gene |
25904
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CCR4-NOT transcription complex, subunit 10
|
| Other Description |
CCR4-NOT transcription complex subunit 10
|
| Swissprots |
Q9H9W0 F8WAF2 Q9H8X1 Q9BU30 Q9UFJ2 Q9H9A5 Q9HAH3 B7Z7L1 Q9H5J7
|
| Accessions |
CAA78605 EAW64434 EAW64435 EAW64436 Q9H9A5 AK021695 BAB13876 AK022576 BAB14108 AK022952 BAB14327 AK023227 BAB14478 AK027026 BAB15629 AK297085 BAH12492 AK298693 BAH12849 AK302196 BAH13647 AK309670 AL117639 CAB56027 BC002928 AAH02928 BC002931 AAH02931 BC006382 BM979742 DB107280 DC394847 DQ597677 DQ892895 ABM83821 DQ896143 ABM87142 EU831494 ACE87181 EU831581 ACE86500 XM_006713084 XP_006713147 XM_006713085 XP_006713148 XM_011533566 XP_011531868 XM_011533567 XP_011531869 XM_011533568 XP_011531870 XM_011533569 XP_011531871 XR_940404 NM_001256741 NP_001243670 NM_001256742 NP_001243671 NM_015442 NP_056257 NR_046352
|
| Function |
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is not required for association of CNOT7 to the CCR4- NOT complex. {ECO:0000269|PubMed:23221646}.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
|
| Top Pathways |
RNA degradation
|
![Western Blot: CNOT10 Overexpression Lysate (Adult Normal) [NBP2-07173] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CNOT10.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9740_CNOT10%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07173-img0001.jpg)