| Gene Symbol |
CIAPIN1
|
| Entrez Gene |
57019
|
| Alt Symbol |
2810413N20Rik, Anamorsin, DRE2, PRO0915
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytokine induced apoptosis inhibitor 1
|
| Other Description |
anamorsin|cytokine-induced apoptosis inhibitor 1|fe-S cluster assembly protein DRE2 homolog|predicted protein of HQ0915
|
| Swissprots |
A8K8B6 O75207 O75206 Q6FI81 Q9H0W1 Q9P1L7
|
| Accessions |
AAC24311 AAC24312 EAW82922 EAW82923 EAW82924 Q6FI81 AF116609 AAF71034 AF248964 AAG44562 AK074263 AK292281 BAF84970 AK295024 BAG58080 AL136613 CAB66548 AM393851 CAL38726 BC002568 AAH02568 BC024196 AAH24196 BC067303 AAH67303 BC071740 AAH71740 BG746807 BJ991015 CA443135 CR533545 CAG38576 EU832335 ACE87592 EU832420 ACE86905 XM_005256061 XP_005256118 XM_005256062 XP_005256119 XM_005256063 XP_005256120 NM_001308347 NP_001295276 NM_001308358 NP_001295287 NM_020313 NP_064709
|
| Function |
Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein NDOR1. {ECO:0000250, ECO:0000269|PubMed:23596212}.
|
| Subcellular Location |
Cytoplasm. Nucleus. Mitochondrion. Mitochondrion intermembrane space {ECO:0000305}. Note=Imported into mitochondria (in vitro).
|
| Tissue Specificity |
Ubiquitously expressed. Highly expressed in heart, liver and pancreas. {ECO:0000269|PubMed:14970183}.
|