Gene Symbol | CORO1C |
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Entrez Gene | 23603 |
Alt Symbol | HCRNN4 |
Species | Human |
Gene Type | protein-coding |
Description | coronin, actin binding protein, 1C |
Other Description | coronin 1C|coronin, actin-binding protein, 1C|coronin-1C|coronin-3 |
Swissprots | Q9NSK5 Q9ULV4 A7MAP0 B3KU12 A7MAP1 |
Accessions | EAW97826 EAW97827 EAW97828 EAW97829 Q9ULV4 AB030656 BAA83077 AB209909 BAD93146 AK023205 BAG51168 AK096363 BAG53274 AK223073 BAD96793 AK297463 BAG59885 AK304839 BAG65582 AK311315 AK316065 BAH14436 AK316504 BAH14875 AL162070 CAB82406 AM849477 CAO94662 AM849478 CAO94663 BC002342 AAH02342 BM677390 DB450956 HQ447934 ADQ32418 Z24726 XM_011538124 XP_011536426 XM_011538125 XP_011536427 XR_944514 NM_001105237 NP_001098707 NM_001276471 NP_001263400 NM_014325 NP_055140 |
Function | May be involved in cytokinesis, motility, and signal transduction. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:12377779}. Cell projection, lamellipodium {ECO:0000269|PubMed:12377779}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12377779}. Note=All isoforms localize in a diffuse and punctate pattern in the cytosol and are highly enriched in F-actin-rich areas. Isoform 3 colocalizes with the thin filaments of the sarcomere and with the postsynaptic area and the junctional sarcoplasm of motor end plates. |
Tissue Specificity | Ubiquitous. |
Coronin 1C CRISPR/Cas9 KO Plasmid (h) - sc-403089 from Santa Cruz Biotechnology
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Coronin 1C HDR Plasmid (h) - sc-403089-HDR from Santa Cruz Biotechnology
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Coronin 1C Double Nickase Plasmid (h) - sc-403089-NIC from Santa Cruz Biotechnology
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Coronin 1C Double Nickase Plasmid (h2) - sc-403089-NIC-2 from Santa Cruz Biotechnology
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Coronin 1C CRISPR Activation Plasmid (h) - sc-403089-ACT from Santa Cruz Biotechnology
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Coronin 1C CRISPR Activation Plasmid (h2) - sc-403089-ACT-2 from Santa Cruz Biotechnology
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Coronin 1C Lentiviral Activation Particles (h) - sc-403089-LAC from Santa Cruz Biotechnology
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Coronin 1C Lentiviral Activation Particles (h2) - sc-403089-LAC-2 from Santa Cruz Biotechnology
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Coronin 1C siRNA (h) - sc-44693 from Santa Cruz Biotechnology
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Coronin 1C shRNA Plasmid (h) - sc-44693-SH from Santa Cruz Biotechnology
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Coronin 1C shRNA (h) Lentiviral Particles - sc-44693-V from Santa Cruz Biotechnology
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Coronin 3 RNAi - H00023603-R01 from Novus Biologicals
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MISSION® esiRNA - EHU057431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6454 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6454 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11222 from Sigma-Aldrich
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CORO1C siRNA (Human) - CRH8391 from Cohesion Biosciences
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CORO1C - MBS8221607 from MyBioSource
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shRNA set against Human CORO1C (NM_014325.2) - SHH268069 from Creative biogene
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shRNA set against Human CORO1C(NM_014325.2) - SHG193717 from Creative biogene
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Human CORO1C siRNA - orb268893 from Biorbyt
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CORO1C shRNA Plasmid (Human) - CHH8391 from Cohesion Biosciences
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CORO1C miRNA 3'UTR clone - MiUTR1H-02370 from Creative biogene
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