Gene Symbol | MND1 |
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Entrez Gene | 84057 |
Alt Symbol | GAJ |
Species | Human |
Gene Type | protein-coding |
Description | meiotic nuclear divisions 1 homolog (S. cerevisiae) |
Other Description | homolog of yeast MND1|meiotic nuclear division protein 1 homolog |
Swissprots | Q9BWT6 B2R5F9 |
Accessions | EAX04964 EAX04965 Q9BWT6 AA542845 AK312172 BAG35106 AY028916 AAK26168 BC032142 AAH32142 BF975093 BG613292 BG758047 BM820228 BM833450 BU533354 DQ891986 ABM82912 DQ895176 ABM86102 XM_005263275 XP_005263332 NM_001253861 NP_001240790 NM_032117 NP_115493 NR_045605 |
Function | Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis (By similarity). Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks. {ECO:0000250|UniProtKB:Q8K396, ECO:0000269|PubMed:16407260}. |
Subcellular Location | Nucleus {ECO:0000305}. |
MND1 CRISPR/Cas9 KO Plasmid (h) - sc-407982 from Santa Cruz Biotechnology
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MND1 HDR Plasmid (h) - sc-407982-HDR from Santa Cruz Biotechnology
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MND1 Double Nickase Plasmid (h) - sc-407982-NIC from Santa Cruz Biotechnology
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MND1 Double Nickase Plasmid (h2) - sc-407982-NIC-2 from Santa Cruz Biotechnology
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MND1 CRISPR Activation Plasmid (h) - sc-407982-ACT from Santa Cruz Biotechnology
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MND1 CRISPR Activation Plasmid (h2) - sc-407982-ACT-2 from Santa Cruz Biotechnology
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MND1 Lentiviral Activation Particles (h) - sc-407982-LAC from Santa Cruz Biotechnology
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MND1 Lentiviral Activation Particles (h2) - sc-407982-LAC-2 from Santa Cruz Biotechnology
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MND1 siRNA (h) - sc-89043 from Santa Cruz Biotechnology
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MND1 shRNA Plasmid (h) - sc-89043-SH from Santa Cruz Biotechnology
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MND1 shRNA (h) Lentiviral Particles - sc-89043-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU024251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14445 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14445 from Sigma-Aldrich
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MND1 siRNA (Human) - CRJ3270 from Cohesion Biosciences
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MND1 shRNA Plasmid (Human) - CHJ3270 from Cohesion Biosciences
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MND1 miRNA 3'UTR clone - MiUTR3H-11874 from Creative biogene
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