| Gene Symbol |
CCT8
|
| Entrez Gene |
10694
|
| Alt Symbol |
C21orf112, Cctq, D21S246, PRED71
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chaperonin containing TCP1, subunit 8 (theta)
|
| Other Description |
CCT-theta|T-complex protein 1 subunit theta|TCP-1-theta|renal carcinoma antigen NY-REN-15
|
| Swissprots |
B4DQH4 B4DEM7 Q4VBP8 P50990 A6NN54
|
| Accessions |
BAA07652 CAB90433 EAX09924 EAX09925 EAX09926 P50990 AK222490 BAD96210 AK293705 BAG57138 AK298801 BAG60936 AK308063 BC005220 BC012584 AAH12584 BC035472 BC072001 AAH72001 BC095470 AAH95470 BP248736 BU932439 D13627 BAA02792 DB301557 DC298601 Z37163 CAA85520 NM_001282907 NP_001269836 NM_001282908 NP_001269837 NM_001282909 NP_001269838 NM_006585 NP_006576
|
| Function |
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. {ECO:0000269|PubMed:20080638}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:20080638}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20080638}.
|
![Western Blot: CCT8 Overexpression Lysate (Adult Normal) [NBL1-08903] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CCT8.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/10188_CCT8%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-08903-img0002.jpg)