Gene Symbol | PPP2R2A |
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Entrez Gene | 5520 |
Alt Symbol | B55A, B55ALPHA, PR52A, PR55A |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 2, regulatory subunit B, alpha |
Other Description | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform|serine/threonine protein phosphatase 2A, 55 KDA regulatory subunit B, alpha isoform|serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform |
Swissprots | B2RBU8 P63151 B4E1T7 |
Accessions | EAW63577 EAW63578 EAW63579 EAW63580 P63151 AI814790 AK095153 AK123721 AK303981 BAG64899 AK314823 BAG37345 AY189686 AAO85219 BC041071 AAH41071 BX440554 CR936829 DB451813 M64929 AAA36490 XM_005273559 XP_005273616 XM_005273560 XP_005273617 XM_011544565 XP_011542867 XM_011544566 XP_011542868 XM_011544567 XP_011542869 XM_011544568 XP_011542870 XM_011544569 XP_011542871 XR_949430 NM_001177591 NP_001171062 NM_002717 NP_002708 |
Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
Tissue Specificity | Expressed in all tissues examined. {ECO:0000269|PubMed:1849734}. |
Top Pathways | Dopaminergic synapse, mRNA surveillance pathway, PI3K-Akt signaling pathway, Hepatitis C, Hippo signaling pathway |
PP2A-B55-α CRISPR/Cas9 KO Plasmid (h) - sc-416837 from Santa Cruz Biotechnology
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PP2A-B55-α HDR Plasmid (h) - sc-416837-HDR from Santa Cruz Biotechnology
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PP2A-B55-α Double Nickase Plasmid (h) - sc-416837-NIC from Santa Cruz Biotechnology
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PP2A-B55-α Double Nickase Plasmid (h2) - sc-416837-NIC-2 from Santa Cruz Biotechnology
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PP2A-B55-α CRISPR Activation Plasmid (h) - sc-416837-ACT from Santa Cruz Biotechnology
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PP2A-B55-α CRISPR Activation Plasmid (h2) - sc-416837-ACT-2 from Santa Cruz Biotechnology
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PP2A-B55-α Lentiviral Activation Particles (h) - sc-416837-LAC from Santa Cruz Biotechnology
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PP2A-B55-α Lentiviral Activation Particles (h2) - sc-416837-LAC-2 from Santa Cruz Biotechnology
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PP2A-B55-α siRNA (h) - sc-39185 from Santa Cruz Biotechnology
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PP2A-B55-α shRNA Plasmid (h) - sc-39185-SH from Santa Cruz Biotechnology
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PP2A-B55-α shRNA (h) Lentiviral Particles - sc-39185-V from Santa Cruz Biotechnology
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PPP2R2A RNAi - H00005520-R01 from Novus Biologicals
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MISSION® esiRNA - EHU231171 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0615 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0613 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0614 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17291 from Sigma-Aldrich
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PPP2R2A siRNA (Human) - CRH3699 from Cohesion Biosciences
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shRNA set against Human PPP2R2A (NM_002717.3) - SHH381384 from Creative biogene
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Human PPP2R2A siRNA - orb264201 from Biorbyt
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PPP2R2A shRNA Plasmid (Human) - CHH3699 from Cohesion Biosciences
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PPP2R2A miRNA 3'UTR clone - MiUTR3H-07234 from Creative biogene
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