Gene Symbol | UPB1 |
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Entrez Gene | 51733 |
Alt Symbol | BUP1 |
Species | Human |
Gene Type | protein-coding |
Description | ureidopropionase, beta |
Other Description | beta-alanine synthase|beta-ureidopropionase|n-carbamoyl-beta-alanine amidohydrolase |
Swissprots | Q9UBR1 Q9UIR3 A3KMF8 |
Accessions | AAF06739 EAW59662 EAW59663 EAW59664 Q9UBR1 AB013885 BAA88634 AF163312 AAF06735 AK024277 BAG51283 AK314727 BAG37269 BC033388 BC131703 AAI31704 BC139840 AAI39841 BC139843 AAI39844 BX537493 CAI46015 CR456375 CAG30261 CR627429 CAH10516 CU013080 CAK54511 CU013368 CAK54810 XM_011530222 XP_011528524 XM_011530223 XP_011528525 XM_011530224 XP_011528526 XM_011530225 XP_011528527 XR_937867 NM_016327 NP_057411 |
Function | Converts N-carbamoyl-beta-aminoisobutyrate and N- carbamoyl-beta-alanine (3-ureidopropanoate) to, respectively, beta-aminoisobutyrate and beta-alanine, ammonia and carbon dioxide. |
Subcellular Location | Cytoplasm. |
Top Pathways | Drug metabolism - other enzymes, Pyrimidine metabolism, beta-Alanine metabolism, Pantothenate and CoA biosynthesis |
BUP-1 CRISPR/Cas9 KO Plasmid (h) - sc-409954 from Santa Cruz Biotechnology
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BUP-1 HDR Plasmid (h) - sc-409954-HDR from Santa Cruz Biotechnology
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BUP-1 Double Nickase Plasmid (h) - sc-409954-NIC from Santa Cruz Biotechnology
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BUP-1 Double Nickase Plasmid (h2) - sc-409954-NIC-2 from Santa Cruz Biotechnology
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BUP-1 CRISPR Activation Plasmid (h) - sc-409954-ACT from Santa Cruz Biotechnology
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BUP-1 CRISPR Activation Plasmid (h2) - sc-409954-ACT-2 from Santa Cruz Biotechnology
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BUP-1 Lentiviral Activation Particles (h) - sc-409954-LAC from Santa Cruz Biotechnology
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BUP-1 Lentiviral Activation Particles (h2) - sc-409954-LAC-2 from Santa Cruz Biotechnology
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BUP-1 siRNA (h) - sc-62028 from Santa Cruz Biotechnology
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BUP-1 shRNA Plasmid (h) - sc-62028-SH from Santa Cruz Biotechnology
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BUP-1 shRNA (h) Lentiviral Particles - sc-62028-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU021691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22514 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22514 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07430 from Sigma-Aldrich
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UPB1 siRNA (Human) - CRH9923 from Cohesion Biosciences
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UPB1 - MBS829318 from MyBioSource
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shRNA set against Human UPB1 (NM_016327.2) - SHH440720 from Creative biogene
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shRNA set against Human UPB1(NM_016327.2) - SHL115518 from Creative biogene
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Human UPB1 siRNA - orb270425 from Biorbyt
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UPB1 shRNA Plasmid (Human) - CHH9923 from Cohesion Biosciences
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UPB1 miRNA 3'UTR clone - MiUTR1H-11024 from Creative biogene
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