Gene Symbol | CDC6 |
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Entrez Gene | 990 |
Alt Symbol | CDC18L, HsCDC18, HsCDC6 |
Species | Human |
Gene Type | protein-coding |
Description | cell division cycle 6 |
Other Description | CDC6 cell division cycle 6 homolog|CDC6-related protein|cdc18-related protein|cell division control protein 6 homolog|cell division cycle 6 homolog|p62(cdc6) |
Swissprots | Q8TB30 Q99741 |
Accessions | AAN10296 CAG24445 EAW60650 EAW60651 Q99741 AA210818 AF022109 AAC52071 AK313620 BAG36382 BC025232 AAH25232 BE296640 BE548194 BF203219 DQ892840 ABM83766 DQ896087 ABM87086 U77949 AAB38317 XM_011525541 XP_011523843 XM_011525542 XP_011523844 NM_001254 NP_001245 |
Function | Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9566895}. Cytoplasm {ECO:0000269|PubMed:9566895}. Note=The protein is nuclear in G1 and cytoplasmic in S-phase cells. |
Top Pathways | Cell cycle |
Cdc6 CRISPR/Cas9 KO Plasmid (h) - sc-400796 from Santa Cruz Biotechnology
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Cdc6 HDR Plasmid (h) - sc-400796-HDR from Santa Cruz Biotechnology
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Cdc6 Double Nickase Plasmid (h) - sc-400796-NIC from Santa Cruz Biotechnology
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Cdc6 Double Nickase Plasmid (h2) - sc-400796-NIC-2 from Santa Cruz Biotechnology
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Cdc6 CRISPR Activation Plasmid (h) - sc-400796-ACT from Santa Cruz Biotechnology
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Cdc6 CRISPR Activation Plasmid (h2) - sc-400796-ACT-2 from Santa Cruz Biotechnology
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Cdc6 Lentiviral Activation Particles (h) - sc-400796-LAC from Santa Cruz Biotechnology
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Cdc6 Lentiviral Activation Particles (h2) - sc-400796-LAC-2 from Santa Cruz Biotechnology
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Cdc6 siRNA (h) - sc-29258 from Santa Cruz Biotechnology
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Cdc6 shRNA Plasmid (h) - sc-29258-SH from Santa Cruz Biotechnology
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Cdc6 shRNA (h) Lentiviral Particles - sc-29258-V from Santa Cruz Biotechnology
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Cdc6 RNAi - H00000990-R01 from Novus Biologicals
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MISSION® esiRNA - EHU024851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5795 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5795 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08907 from Sigma-Aldrich
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CDC6 siRNA (Human) - CRH0705 from Cohesion Biosciences
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CDC6 - MBS8236818 from MyBioSource
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shRNA set against Human CDC6 (NM_001254.3) - SHH259969 from Creative biogene
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shRNA set against Human CDC6(NM_001254.3) - SHG162073 from Creative biogene
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Human CDC6 siRNA - orb261207 from Biorbyt
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CDC6 shRNA Plasmid (Human) - CHH0705 from Cohesion Biosciences
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CDC6 miRNA 3'UTR clone - MiUTR1H-01964 from Creative biogene
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