| Gene Symbol |
pldA
|
| Entrez Gene |
8622829
|
| Alt Symbol |
DDBDRAFT_0203964, DDBDRAFT_0231506, DDB_0203964, DDB_0231506
|
| Species |
Dictyostelium discoideum
|
| Gene Type |
protein-coding
|
| Description |
phospholipase D1
|
| Other Description |
-
|
| Swissprots |
Q54UK0
|
| Accessions |
EAL66812 XM_635684 XP_640776
|
| Function |
Plays a role in cell growth. Hydrolyzes membrane phospholipids, such as PtdCho free headgroup and PtdOH (phosphatidic acid; signaling molecule on its own). Involved in the inhibition of actin-based motility and endocytosis. Its inhibition causes complete collapse of F-actin organization. {ECO:0000269|PubMed:15769249, ECO:0000269|PubMed:6498208, ECO:0000269|PubMed:8394342}.
|
| Top Pathways |
Endocytosis, Ether lipid metabolism, Glycerophospholipid metabolism
|