Gene Symbol | AKAP6 |
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Entrez Gene | 9472 |
Alt Symbol | ADAP100, ADAP6, AKAP100, PRKA6, mAKAP |
Species | Human |
Gene Type | protein-coding |
Description | A kinase (PRKA) anchor protein 6 |
Other Description | A-kinase anchor protein 100 kDa|A-kinase anchor protein 6|AKAP 100|AKAP-6|protein kinase A anchoring protein 6|protein kinase A-anchoring protein 6 |
Swissprots | A7E242 A7E2D4 Q13023 O15028 |
Accessions | EAW65931 EAW65932 EAW65933 Q13023 AB002309 BAA20770 AK094160 BC137232 AAI37233 BC137233 AAI37234 BC150185 AAI50186 BC150288 AAI50289 BC154413 AAI54414 BP230135 U17195 AAA92354 XM_005268219 XP_005268276 XM_011537378 XP_011535680 XM_011537379 XP_011535681 XM_011537380 XP_011535682 XM_011537381 XP_011535683 XM_011537382 XP_011535684 XM_011537383 XP_011535685 NM_004274 NP_004265 |
Function | Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes. |
Subcellular Location | Sarcoplasmic reticulum. Nucleus membrane. Note=In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences. |
Tissue Specificity | Highly expressed in cardiac and skeletal muscle, followed by brain. |
AKAP 6 CRISPR/Cas9 KO Plasmid (h) - sc-407296 from Santa Cruz Biotechnology
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AKAP 6 HDR Plasmid (h) - sc-407296-HDR from Santa Cruz Biotechnology
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AKAP 100 Double Nickase Plasmid (h) - sc-407296-NIC from Santa Cruz Biotechnology
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AKAP 6 Double Nickase Plasmid (h2) - sc-407296-NIC-2 from Santa Cruz Biotechnology
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AKAP 100 CRISPR Activation Plasmid (h) - sc-407296-ACT from Santa Cruz Biotechnology
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AKAP 6 CRISPR Activation Plasmid (h2) - sc-407296-ACT-2 from Santa Cruz Biotechnology
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AKAP 100 Lentiviral Activation Particles (h) - sc-407296-LAC from Santa Cruz Biotechnology
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AKAP 6 Lentiviral Activation Particles (h2) - sc-407296-LAC-2 from Santa Cruz Biotechnology
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AKAP 6 siRNA (h) - sc-45630 from Santa Cruz Biotechnology
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AKAP 6 shRNA Plasmid (h) - sc-45630-SH from Santa Cruz Biotechnology
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AKAP 6 shRNA (h) Lentiviral Particles - sc-45630-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU004251 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3012 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3012 from Sigma-Aldrich
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AKAP6 siRNA (Human) - CRH6287 from Cohesion Biosciences
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AKAP6 - MBS8203577 from MyBioSource
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shRNA set against Human Akap6 (NM_004274.4) - SHH234298 from Creative biogene
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Human AKAP6 siRNA - orb266789 from Biorbyt
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AKAP6 shRNA Plasmid (Human) - CHH6287 from Cohesion Biosciences
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AKAP6 miRNA 3'UTR clone - MiUTR4H-TG00240 from Creative biogene
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