| Gene Symbol |
MPV17
|
| Entrez Gene |
4358
|
| Alt Symbol |
MTDPS6, SYM1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
MpV17 mitochondrial inner membrane protein
|
| Other Description |
Mpv17, human homolog of glomerulosclerosis and nephrotic syndrome|protein Mpv17
|
| Swissprots |
Q53SY2 D6W555 P39210 Q96B08
|
| Accessions |
AAB25210 AAC24205 AAD14014 AAY24298 ADP91854 ADP91855 ADP91856 ADP91857 ADP91858 ADP91859 ADP91860 ADP91861 ADP91862 ADP91863 ADP91864 ADP91865 ADP91866 ADP91867 ADP91868 ADP91869 ADP91870 ADP91871 ADP91872 ADP91873 ADP91874 ADP91875 ADP91876 ADP91877 ADP91878 ADP91879 ADP91880 ADP91881 ADP91882 ADP91883 ADP91884 ADP91885 ADP91886 ADP91887 ADP91888 ADP91889 ADP91890 ADP91891 ADP91892 ADP91893 CAH33966 EAX00597 EAX00598 EAX00599 EAX00600 EAX00601 EAX00602 EAX00603 EAX00604 P39210 AF088036 AK093305 AK123373 BC001115 AAH01115 BC016289 AAH16289 BG714998 BI602840 DQ892279 ABM83205 DQ895479 ABM86405 X76538 CAA54047 XM_005264326 XP_005264383 XM_005264327 XP_005264384 XM_006712021 XP_006712084 NM_002437 NP_002428
|
| Function |
Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:16582907, ECO:0000269|PubMed:16582910}; Multi- pass membrane protein {ECO:0000269|PubMed:16582907, ECO:0000269|PubMed:16582910}.
|
| Tissue Specificity |
Ubiquitous. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain and heart. {ECO:0000269|PubMed:16582910}.
|
| Top Pathways |
Peroxisome
|
![Western Blot: MPV17 Overexpression Lysate (Adult Normal) [NBL1-13211] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MPV17.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2947_MPV17%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13211-img0002.jpg)