| Gene Symbol | MGAT1 |
|---|---|
| Entrez Gene | 4245 |
| Alt Symbol | GLCNAC-TI, GLCT1, GLYT1, GNT-1, GNT-I, MGAT |
| Species | Human |
| Gene Type | protein-coding |
| Description | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| Other Description | N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I|alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase|glcNAc-T I |
| Swissprots | D3DWR1 Q6IBE3 B3KRU8 A8K404 P26572 |
| Accessions | AAA75523 EAW53739 EAW53740 EAW53741 EAW53742 EAW53743 EAW53744 EAW53745 P26572 AB209239 BAD92476 AF289558 AAL55742 AK057194 BAG51880 AK075429 BAC11616 AK090523 BAG52177 AK092256 BAG52510 AK094130 BAG52821 AK290769 BAF83458 BC003575 AAH03575 BG337235 CA426780 CN409895 CR456861 CAG33142 DB270226 DC383950 DQ892503 ABM83429 DQ895716 ABM86642 M55621 AAA52563 XM_005265915 XP_005265972 XM_005265916 XP_005265973 XM_006714866 XP_006714929 XM_011534559 XP_011532861 XM_011534560 XP_011532862 XM_011534561 XP_011532863 XM_011534562 XP_011532864 XM_011534563 XP_011532865 NM_001114617 NP_001108089 NM_001114618 NP_001108090 NM_001114619 NP_001108091 NM_001114620 NP_001108092 NM_002406 NP_002397 |
| Function | Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. |
| Subcellular Location | Golgi apparatus membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Appears to be present in all tissues. |
| Top Pathways | N-Glycan biosynthesis |
GnT-I CRISPR/Cas9 KO Plasmid (h) - sc-409648 from Santa Cruz Biotechnology
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GnT-I HDR Plasmid (h) - sc-409648-HDR from Santa Cruz Biotechnology
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GnT-I Double Nickase Plasmid (h) - sc-409648-NIC from Santa Cruz Biotechnology
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GnT-I Double Nickase Plasmid (h2) - sc-409648-NIC-2 from Santa Cruz Biotechnology
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GnT-I CRISPR Activation Plasmid (h) - sc-409648-ACT from Santa Cruz Biotechnology
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GnT-I CRISPR Activation Plasmid (h2) - sc-409648-ACT-2 from Santa Cruz Biotechnology
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GnT-I Lentiviral Activation Particles (h) - sc-409648-LAC from Santa Cruz Biotechnology
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GnT-I Lentiviral Activation Particles (h2) - sc-409648-LAC-2 from Santa Cruz Biotechnology
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GnT-I siRNA (h) - sc-106893 from Santa Cruz Biotechnology
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GnT-I shRNA Plasmid (h) - sc-106893-SH from Santa Cruz Biotechnology
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GnT-I shRNA (h) Lentiviral Particles - sc-106893-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU091161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13272 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13272 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08126 from Sigma-Aldrich
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MGAT1 siRNA (Human) - CRH2885 from Cohesion Biosciences
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shRNA set against Human Mgat1 (NM_002406.3) - SHH341339 from Creative biogene
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shRNA set against Human MGAT1(NM_002406.3) - SHH187175 from Creative biogene
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Human MGAT1 siRNA - orb263387 from Biorbyt
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MGAT1 shRNA Plasmid (Human) - CHH2885 from Cohesion Biosciences
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MGAT1 miRNA 3'UTR clone - MiUTR1H-06242 from Creative biogene
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MGAT1 miRNA 3'UTR clone - MiUTR3H-01504 from Creative biogene
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MGAT1 miRNA 3'UTR clone - MiUTR3H-01505 from Creative biogene
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MGAT1 miRNA 3'UTR clone - MiUTR3H-01506 from Creative biogene
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MGAT1 miRNA 3'UTR clone - MiUTR3H-01507 from Creative biogene
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