Gene Symbol | G6PD |
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Entrez Gene | 2539 |
Alt Symbol | G6PD1 |
Species | Human |
Gene Type | protein-coding |
Description | glucose-6-phosphate dehydrogenase |
Other Description | glucose-6-phosphate 1-dehydrogenase |
Swissprots | Q96PQ2 Q16000 Q8IU88 Q8IU70 Q16765 Q8IUA6 P11413 D3DWX9 |
Accessions | AAA63175 AAA92653 AAB20299 AAB59390 AAL27011 AAN76367 AAN76368 AAN76369 AAN76370 AAN76371 AAN76372 AAN76373 AAN76374 AAN76375 AAN76376 AAN76377 AAN76378 AAN76379 AAN76380 AAN76381 AAN76382 AAN76383 AAN76384 AAN76385 AAN76386 AAN76387 AAN76388 AAN76389 AAN76390 AAN76391 AAN76392 AAN76393 AAN76394 AAN76395 AAN76396 AAN76397 AAN76398 AAN76399 AAN76400 AAN76401 AAN76402 AAN76403 AAN76404 AAN76405 AAN76406 AAN76407 AAN76408 AAN76409 AAN76410 AAN76411 AAN76412 AAN76413 ABB90566 ABC25732 ABC25737 ABC25742 ABC25747 ABC25752 ABC25757 ABC25761 ABC25766 ABC25771 ABC25776 ABC25781 ABC25786 ABC25791 ABC25796 ABC25801 ABC25806 ABC25811 ABC25816 ABC25821 ABC25826 ABC25831 ABC25836 ABC25841 ABC25846 ABC25851 ABC25856 ABC25861 ABC25866 ABC25871 ABC25876 ABC25881 ABC25886 ABC25891 ABC25896 ABC25901 ABC25906 ABC25911 ABC25916 ABC25921 ABC25926 ABC25931 ABC25936 ABC25941 ABC25946 ABC25951 ABC25956 ABC25961 ABC25966 ABC25971 ABC25976 ABC25981 ABH03564 ABH03565 ABH03566 ABH03567 ABH03568 ABH03569 ABI23563 ABM66444 AFK75975 BAH01719 CAA37811 CAA39089 CAS91929 CAS92163 CBF59097 CBN60799 CBN62406 CBN63835 CBN64257 CBN66061 CBN68546 CBN71894 CBU84341 EAW72682 EAW72683 EAW72684 EAW72685 EAW72686 EAW72687 P11413 AK292304 BAF84993 AK302341 BAG63669 AL560686 BC000337 AAH00337 BU589629 DC394789 DQ892219 ABM83145 DQ895415 ABM86341 M19866 AAA52501 M21248 AAA52500 M27940 AAA52504 S58359 AAB26169 X03674 CAA27309 XM_005274657 XP_005274714 XM_005274658 XP_005274715 XM_011531132 XP_011529434 NM_000402 NP_000393 NM_001042351 NP_001035810 |
Function | Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis. {ECO:0000269|PubMed:15858258, ECO:0000269|PubMed:24769394}. |
Tissue Specificity | Isoform Long is found in lymphoblasts, granulocytes and sperm. |
Top Pathways | Pentose phosphate pathway, Central carbon metabolism in cancer, Glutathione metabolism, Carbon metabolism |
G6PD (D5D2) Rabbit mAb - 12263 from Cell Signaling Technology
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Glucose-6-Phosphate Dehydrogenase Antibody - 8866 from Cell Signaling Technology
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G6PD (G-12) - sc-373886 from Santa Cruz Biotechnology
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G6PD (C-17) - sc-46968 from Santa Cruz Biotechnology
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G6PD (G-6) - sc-373887 from Santa Cruz Biotechnology
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G6PD (H-160) - sc-67165 from Santa Cruz Biotechnology
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G6PD (N-12) - sc-46971 from Santa Cruz Biotechnology
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Anti-Glucose 6 Phosphate Dehydrogenase antibody - ab993 from Abcam
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Anti-Glucose 6 Phosphate Dehydrogenase antibody - ab106810 from Abcam
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Anti-Glucose 6 Phosphate Dehydrogenase antibody - ab84087 from Abcam
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Anti-Glucose 6 Phosphate Dehydrogenase antibody - ab61704 from Abcam
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Anti-Glucose 6 Phosphate Dehydrogenase antibody - ab80362 from Abcam
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Anti-Glucose 6 Phosphate Dehydrogenase antibody [5E12] - ab119949 from Abcam
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Anti-Glucose 6 Phosphate Dehydrogenase antibody [EPR6291] - ab124738 from Abcam
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Anti-Glucose 6 Phosphate Dehydrogenase antibody [EPR6292] - ab133525 from Abcam
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Anti-G6PD Antibody - LS-C192780 from LifeSpan Bioscience
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Anti-G6PD Antibody (aa1-515, FITC) - LS-C305659 from LifeSpan Bioscience
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Anti-G6PD Antibody (aa1-515, FITC) - LS-C305660 from LifeSpan Bioscience
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Anti-G6PD Antibody (Internal, clone EPR6291) - LS-C138702 from LifeSpan Bioscience
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Anti-G6PD Antibody (aa50-100) - LS-C287293 from LifeSpan Bioscience
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Anti-G6PD Antibody (aa297-326) - LS-C166304 from LifeSpan Bioscience
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Anti-G6PD Antibody (clone 3H5) - LS-C197258 from LifeSpan Bioscience
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Anti-G6PD Antibody - LS-C310420 from LifeSpan Bioscience
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Anti-G6PD Antibody (aa1-515) - LS-C294210 from LifeSpan Bioscience
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Anti-G6PD Antibody (aa1-515) - LS-C294211 from LifeSpan Bioscience
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