Gene Symbol | DEPTOR |
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Entrez Gene | 64798 |
Alt Symbol | DEP.6, DEPDC6 |
Species | Human |
Gene Type | protein-coding |
Description | DEP domain containing MTOR-interacting protein |
Other Description | DEP domain containing 6|DEP domain containing mTOR interacting protein|DEP domain-containing mTOR-interacting protein|DEP domain-containing protein 6 |
Swissprots | Q9H0R7 Q96EQ1 B4DN97 E7EV87 Q9HA07 Q9H894 B2RCL9 Q8TB45 |
Accessions | EAW91997 Q8TB45 AK022403 AK022490 BAB14054 AK023916 BAB14723 AK225168 AK225675 AK297822 BAG60159 AK315175 BAG37616 AL136678 CAB66613 AM392576 CAL37454 AM393333 CAL38211 BC012040 AAH12040 BC024746 AAH24746 DA622978 NM_001283012 NP_001269941 NM_022783 NP_073620 |
Function | Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes. {ECO:0000269|PubMed:19446321}. |
DEPTOR CRISPR/Cas9 KO Plasmid (h) - sc-402253 from Santa Cruz Biotechnology
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DEPTOR HDR Plasmid (h) - sc-402253-HDR from Santa Cruz Biotechnology
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DEPTOR Double Nickase Plasmid (h) - sc-402253-NIC from Santa Cruz Biotechnology
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DEPTOR Double Nickase Plasmid (h2) - sc-402253-NIC-2 from Santa Cruz Biotechnology
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DEPTOR CRISPR Activation Plasmid (h) - sc-402253-ACT from Santa Cruz Biotechnology
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DEPTOR CRISPR Activation Plasmid (h2) - sc-402253-ACT-2 from Santa Cruz Biotechnology
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DEPTOR Lentiviral Activation Particles (h) - sc-402253-LAC from Santa Cruz Biotechnology
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DEPTOR Lentiviral Activation Particles (h2) - sc-402253-LAC-2 from Santa Cruz Biotechnology
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DEPTOR siRNA (h) - sc-77660 from Santa Cruz Biotechnology
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DEPTOR shRNA Plasmid (h) - sc-77660-SH from Santa Cruz Biotechnology
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DEPTOR shRNA (h) Lentiviral Particles - sc-77660-V from Santa Cruz Biotechnology
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DEPTOR/DEPDC6 RNAi - H00064798-R01 from Novus Biologicals
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MISSION® esiRNA - EHU143391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7153 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7153 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07313 from Sigma-Aldrich
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DEPTOR siRNA (Human) - CRJ2099 from Cohesion Biosciences
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DEPTOR - MBS8212874 from MyBioSource
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shRNA set against Human DEPTOR (NM_022783.2) - SHH277189 from Creative biogene
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Human DEPTOR siRNA - orb272600 from Biorbyt
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DEPTOR shRNA Plasmid (Human) - CHJ2099 from Cohesion Biosciences
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DEPTOR miRNA 3'UTR clone - MiUTR3H-12708 from Creative biogene
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