| Gene Symbol |
GGA3
|
| Entrez Gene |
23163
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
golgi-associated, gamma adaptin ear containing, ARF binding protein 3
|
| Other Description |
ADP-ribosylation factor-binding protein GGA3|Golgi-localized, gamma ear-containing, ARF-binding protein 3
|
| Swissprots |
Q9NZ52 B7Z7E2 Q9UJY3 Q6IS16 B7Z7M9 J3KRN0 Q15017
|
| Accessions |
EAW89252 EAW89253 EAW89254 EAW89255 EAW89256 EAW89257 EAW89258 EAW89259 EAW89260 Q9NZ52 AF190864 AAF05709 AF219138 AAF42848 AF219139 AAF42849 AK124541 AK291651 BAF84340 AK291685 BAF84374 AK293291 BAH11485 AK296843 BAH12442 AK301895 BAH13578 AK302278 BAH13665 AK302423 BAH13705 AK304692 BAH14238 AL833603 BC051732 BC063285 BC070044 AAH70044 BM981305 CB240770 D63876 BAA09926 DA312660 HY030361 XM_011524563 XP_011522865 XM_011524564 XP_011522866 XM_011524565 XP_011522867 XM_011524566 XP_011522868 XM_011524567 XP_011522869 XM_011524568 XP_011522870 XM_011524569 XP_011522871 XM_011524570 XP_011522872 NM_001172703 NP_001166174 NM_001172704 NP_001166175 NM_001291641 NP_001278570 NM_001291642 NP_001278571 NM_014001 NP_054720 NM_138619 NP_619525
|
| Function |
Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif. {ECO:0000269|PubMed:11301005}.
|
| Subcellular Location |
Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:15039775}; Peripheral membrane protein {ECO:0000269|PubMed:15039775}. Endosome membrane {ECO:0000269|PubMed:15039775}; Peripheral membrane protein {ECO:0000269|PubMed:15039775}.
|
| Tissue Specificity |
Ubiquitously expressed.
|
| Top Pathways |
Lysosome
|