Gene Symbol | HAS3 |
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Entrez Gene | 3038 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | hyaluronan synthase 3 |
Other Description | HA synthase 3|hyaluronate synthase 3|hyaluronic acid synthase 3 |
Swissprots | O00219 Q8WTZ0 Q9NYP0 A8K5T5 |
Accessions | AAC51209 EAW83247 EAW83248 O00219 AF232772 AAF36984 AF234839 AAK73797 AK291400 BAF84089 AW294351 BC021853 AAH21853 FJ648810 ACN41863 FJ648811 ACN41864 XM_005255921 XP_005255978 XM_011523061 XP_011521363 NM_001199280 NP_001186209 NM_005329 NP_005320 NM_138612 NP_619515 |
Function | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
HAS3 CRISPR/Cas9 KO Plasmid (h) - sc-401531 from Santa Cruz Biotechnology
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HAS3 HDR Plasmid (h) - sc-401531-HDR from Santa Cruz Biotechnology
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HAS3 Double Nickase Plasmid (h) - sc-401531-NIC from Santa Cruz Biotechnology
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HAS3 Double Nickase Plasmid (h2) - sc-401531-NIC-2 from Santa Cruz Biotechnology
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HAS3 CRISPR Activation Plasmid (h) - sc-401531-ACT from Santa Cruz Biotechnology
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HAS3 CRISPR Activation Plasmid (h2) - sc-401531-ACT-2 from Santa Cruz Biotechnology
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HAS3 Lentiviral Activation Particles (h) - sc-401531-LAC from Santa Cruz Biotechnology
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HAS3 Lentiviral Activation Particles (h2) - sc-401531-LAC-2 from Santa Cruz Biotechnology
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HAS3 siRNA (h) - sc-45295 from Santa Cruz Biotechnology
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HAS3 shRNA Plasmid (h) - sc-45295-SH from Santa Cruz Biotechnology
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HAS3 shRNA (h) Lentiviral Particles - sc-45295-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU156741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9879 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9879 from Sigma-Aldrich
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HAS3 siRNA (Human) - CRH2066 from Cohesion Biosciences
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HAS3 - MBS8201891 from MyBioSource
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shRNA set against Human HAS3 (NM_005329.2) - SHH310393 from Creative biogene
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shRNA set against Human HAS3(NM_005329.2) - SHH114329 from Creative biogene
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HAS3 shRNA Plasmid (Human) - CHH2066 from Cohesion Biosciences
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HAS3 miRNA 3'UTR clone - MiUTR1H-04380 from Creative biogene
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HAS3 miRNA 3'UTR clone - MiUTR3H-04974 from Creative biogene
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