Gene Symbol | CSH1 |
---|---|
Entrez Gene | 1442 |
Alt Symbol | CS-1, CSA, CSMT, PL, hCS-1, hCS-A |
Species | Human |
Gene Type | protein-coding |
Description | chorionic somatomammotropin hormone 1 (placental lactogen) |
Other Description | choriomammotropin|chorionic somatomammotropin A|chorionic somatomammotropin hormone 1|chorionic somatomammotropin-1|placental lactogen |
Swissprots | Q14407 Q0VDB1 P01243 P0DML2 |
Accessions | AAA52115 AAA52551 AAO64720 ABZ88716 ABZ88717 ABZ88718 CBH19248 EAW94235 EAW94236 EAW94237 EAW94241 EAW94243 EAW94254 EAW94257 EAW94259 P0DML2 AK291587 BAF84276 AU134786 BC002717 AAH02717 BC005921 AAH05921 BC020756 AAH20756 BC057768 AAH57768 BC062775 AAH62775 BG436049 BQ004002 BT006926 AAP35572 HQ447195 ADQ31682 J00118 AAA98621 M25118 AAA35721 M35419 AAP03711 V00593 CAA23840 NM_001317 NP_001308 NM_022640 NM_022641 |
Function | Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. {ECO:0000269|PubMed:16546209}. |
Subcellular Location | Secreted. |
Top Pathways | Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction |
CSH1 CRISPR/Cas9 KO Plasmid (h) - sc-401213 from Santa Cruz Biotechnology
|
||||||||
CSH1 HDR Plasmid (h) - sc-401213-HDR from Santa Cruz Biotechnology
|
||||||||
CSH1 Double Nickase Plasmid (h) - sc-401213-NIC from Santa Cruz Biotechnology
|
||||||||
CSH1 Double Nickase Plasmid (h2) - sc-401213-NIC-2 from Santa Cruz Biotechnology
|
||||||||
CSH1 CRISPR Activation Plasmid (h) - sc-401213-ACT from Santa Cruz Biotechnology
|
||||||||
CSH1 CRISPR Activation Plasmid (h2) - sc-401213-ACT-2 from Santa Cruz Biotechnology
|
||||||||
CSH1 Lentiviral Activation Particles (h) - sc-401213-LAC from Santa Cruz Biotechnology
|
||||||||
CSH1 Lentiviral Activation Particles (h2) - sc-401213-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Placental lactogen I siRNA (h) - sc-77032 from Santa Cruz Biotechnology
|
||||||||
Placental lactogen I shRNA Plasmid (h) - sc-77032-SH from Santa Cruz Biotechnology
|
||||||||
Placental lactogen I shRNA (h) Lentiviral Particles - sc-77032-V from Santa Cruz Biotechnology
|
||||||||
Placental Lactogen/CSH1 RNAi - H00001442-R03 from Novus Biologicals
|
||||||||
Placental Lactogen/CSH1 RNAi - H00001442-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU128341 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN6635 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6635 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02343 from Sigma-Aldrich
|
||||||||
CSH1 siRNA (Human) - CRH1016 from Cohesion Biosciences
|
||||||||
Placental Lactogen/CSH1 RNAi - H00001442-R02 from Novus Biologicals
|
||||||||
CSH1 - MBS8211492 from MyBioSource
|
||||||||
CSH2 - MBS8235824 from MyBioSource
|
||||||||
CSH1 CRISPR/Cas9 KO Plasmid (h2) - sc-401213-KO-2 from Santa Cruz Biotechnology
|
||||||||
CSH1 HDR Plasmid (h2) - sc-401213-HDR-2 from Santa Cruz Biotechnology
|
||||||||
shRNA set against Human CSH1 (NM_001317.5) - SHH270325 from Creative biogene
|
||||||||
Human CSH2 siRNA - orb261519 from Biorbyt
|