Gene Symbol | VSTM1 |
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Entrez Gene | 284415 |
Alt Symbol | SIRL-1, SIRL1, UNQ3033 |
Species | Human |
Gene Type | protein-coding |
Description | V-set and transmembrane domain containing 1 |
Other Description | LAIR homolog|OSCAR-like transcript-1|V-set and transmembrane domain-containing protein 1|signal inhibitory receptor on leukocytes-1 |
Swissprots | Q496B7 D2DJS4 Q496B6 Q6UX27 D2DJS3 B6A8C6 |
Accessions | EAW72173 Q6UX27 AI457604 AY358542 AAQ88906 BC100942 AAI00943 BC100943 AAI00944 BG189223 BQ446114 DQ479397 ABF19807 FJ584316 ACU00108 FJ584317 ACU00109 FJ584318 ACU00110 FJ584319 ACU00111 FJ584320 ACU00112 FJ882051 ACZ51446 FN398145 CAZ61324 XM_011526845 XP_011525147 XM_011526846 XP_011525148 XM_011526847 XP_011525149 XM_011526848 XP_011525150 XM_011526849 XP_011525151 XM_011547111 XP_011545413 XM_011547112 XP_011545414 XM_011547113 XP_011545415 XM_011547114 XP_011545416 XM_011547115 XP_011545417 XM_011547520 XP_011545822 XM_011547521 XP_011545823 XM_011547522 XP_011545824 XM_011547523 XP_011545825 XM_011547524 XP_011545826 XM_011547770 XP_011546072 XM_011547771 XP_011546073 XM_011547772 XP_011546074 XM_011547773 XP_011546075 XM_011547774 XP_011546076 XM_011547972 XP_011546274 XM_011547973 XP_011546275 XM_011547974 XP_011546276 XM_011547975 XP_011546277 XM_011547976 XP_011546278 XM_011548149 XP_011546451 XM_011548150 XP_011546452 XM_011548151 XP_011546453 XM_011548152 XP_011546454 XM_011548153 XP_011546455 XM_011548342 XP_011546644 XM_011548343 XP_011546645 XM_011548344 XP_011546646 XM_011548345 XP_011546647 XM_011548346 XP_011546648 XM_011548555 XP_011546857 XM_011548556 XP_011546858 XM_011548557 XP_011546859 XM_011548558 XP_011546860 XM_011548559 XP_011546861 XM_011548607 XP_011546909 XM_011548608 XP_011546910 XM_011548609 XP_011546911 XM_011548610 XP_011546912 XM_011548611 XP_011546913 XM_011548700 XP_011547002 XM_011548701 XP_011547003 XM_011548702 XP_011547004 XM_011548703 XP_011547005 XM_011548704 XP_011547006 XR_430197 XR_431003 XR_431064 XR_431089 XR_431098 XR_935808 XR_952191 XR_952526 XR_952758 XR_952759 XR_952911 XR_952912 XR_952988 XR_952989 XR_953062 XR_953063 XR_953131 XR_953149 XR_953150 XR_953172 NM_001288791 NP_001275720 NM_001288792 NP_001275721 NM_001288793 NP_001275722 NM_198481 NP_940883 NR_110142 |
Function | Isoform 2: Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17). |
Subcellular Location | Isoform 1: Membrane {ECO:0000305}; Single- pass membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells. {ECO:0000269|PubMed:20375307}. |
VSTM1 CRISPR/Cas9 KO Plasmid (h) - sc-410411 from Santa Cruz Biotechnology
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VSTM1 HDR Plasmid (h) - sc-410411-HDR from Santa Cruz Biotechnology
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VSTM1 Double Nickase Plasmid (h) - sc-410411-NIC from Santa Cruz Biotechnology
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VSTM1 Double Nickase Plasmid (h2) - sc-410411-NIC-2 from Santa Cruz Biotechnology
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VSTM1 CRISPR Activation Plasmid (h) - sc-410411-ACT from Santa Cruz Biotechnology
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VSTM1 CRISPR Activation Plasmid (h2) - sc-410411-ACT-2 from Santa Cruz Biotechnology
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VSTM1 Lentiviral Activation Particles (h) - sc-410411-LAC from Santa Cruz Biotechnology
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VSTM1 Lentiviral Activation Particles (h2) - sc-410411-LAC-2 from Santa Cruz Biotechnology
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VSTM1 siRNA (h) - sc-97570 from Santa Cruz Biotechnology
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VSTM1 shRNA Plasmid (h) - sc-97570-SH from Santa Cruz Biotechnology
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VSTM1 shRNA (h) Lentiviral Particles - sc-97570-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22745 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22745 from Sigma-Aldrich
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VSTM1 siRNA (Human) - CRJ7021 from Cohesion Biosciences
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VSTM1 - MBS8239458 from MyBioSource
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shRNA set against Human VSTM1 (NM_198481.3) - SHH445268 from Creative biogene
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Human VSTM1 siRNA - orb277522 from Biorbyt
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VSTM1 shRNA Plasmid (Human) - CHJ7021 from Cohesion Biosciences
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VSTM1 miRNA 3'UTR clone - MiUTR1H-11174 from Creative biogene
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