Gene Symbol | SPACA4 |
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Entrez Gene | 171169 |
Alt Symbol | SAMP14 |
Species | Human |
Gene Type | protein-coding |
Description | sperm acrosome associated 4 |
Other Description | sperm acrosomal membrane protein 14|sperm acrosomal membrane-associated protein 14|sperm acrosome membrane-associated protein 4 |
Swissprots | Q8TDM5 |
Accessions | CAI93415 CBH19451 CBH30621 EAW52357 Q8TDM5 AF353721 AAL83950 AY358387 AAQ88753 BC047334 AAH47334 NM_133498 NP_598005 |
Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:12788941}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:12788941}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:12788941}. Note=Expressed in acrosomal matrix and outer and inner acrosomal membranes. |
Tissue Specificity | Testis specific. Expressed in spermatozoa. {ECO:0000269|PubMed:12788941}. |
SPACA4 CRISPR/Cas9 KO Plasmid (h) - sc-417661 from Santa Cruz Biotechnology
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SPACA4 HDR Plasmid (h) - sc-417661-HDR from Santa Cruz Biotechnology
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SPACA4 Double Nickase Plasmid (h) - sc-417661-NIC from Santa Cruz Biotechnology
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SPACA4 Double Nickase Plasmid (h2) - sc-417661-NIC-2 from Santa Cruz Biotechnology
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SPACA4 CRISPR Activation Plasmid (h) - sc-417661-ACT from Santa Cruz Biotechnology
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SPACA4 CRISPR Activation Plasmid (h2) - sc-417661-ACT-2 from Santa Cruz Biotechnology
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SPACA4 Lentiviral Activation Particles (h) - sc-417661-LAC from Santa Cruz Biotechnology
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SPACA4 Lentiviral Activation Particles (h2) - sc-417661-LAC-2 from Santa Cruz Biotechnology
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SPACA4 siRNA (h) - sc-97587 from Santa Cruz Biotechnology
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SPACA4 shRNA Plasmid (h) - sc-97587-SH from Santa Cruz Biotechnology
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SPACA4 shRNA (h) Lentiviral Particles - sc-97587-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU137301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20379 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20379 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03069 from Sigma-Aldrich
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SPACA4 siRNA (Human) - CRJ6138 from Cohesion Biosciences
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SPACA4 - MBS8225865 from MyBioSource
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shRNA set against Human SPACA4 (NM_133498.2) - SHH415732 from Creative biogene
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Human SPACA4 siRNA - orb276639 from Biorbyt
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SPACA4 shRNA Plasmid (Human) - CHJ6138 from Cohesion Biosciences
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SPACA4 miRNA 3'UTR clone - MiUTR1H-09785 from Creative biogene
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