Gene Symbol | RHCE |
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Entrez Gene | 6006 |
Alt Symbol | CD240CE, RH, RH30A, RHC, RHE, RHIXB, RHPI, Rh4, RhIVb(J), RhVI, RhVIII |
Species | Human |
Gene Type | protein-coding |
Description | Rh blood group, CcEe antigens |
Other Description | RHCE blood group variant Crawford antigen Rh43|Rh blood group C antigen|Rh blood group antigen Evans|Rh blood group protein|Rh polypeptide I|Rhesus blood group CE protein|Rhesus blood group E antigen|Rhesus blood group Rhce antigen|Rhesus system C and E polypeptides|blood group Rh(CE) polypeptide|blood group RhCcEe antigen|rh polypeptide 1|rhesus C/E antigens|rhesus blood group antigen, RhC antigen|rhesus blood group little e antigen|silenced Rh blood group CcEe antigen|truncated RHCE |
Swissprots | Q2MJW0 B7UDF9 Q9UD14 Q8IZT4 P18577 Q02165 B7UDF5 Q7RU06 Q3LTM6 B7UDF8 Q02163 B7UDG2 Q8IZT3 Q16160 B7UDF6 Q9UD15 Q9UD13 B7UDG1 B7UDF7 Q9UD74 Q2VC86 B7UDG0 Q9UPN0 B7UDG3 Q6J2U3 A7DW68 B7UDF3 Q8IZT5 Q9UD73 Q6AZX5 Q9UEC2 Q9UEC3 Q8IZT2 Q02164 B7UDF4 Q9UD16 |
Accessions | AAB39601 AAC18093 AAC18094 AAD14061 AAM46623 AAX33314 ABE77176 ACK75562 ACK75563 ACK75564 ACK75565 ACK75566 ACK75567 ACK75568 ACK75569 ACK75570 ACK75571 ACK75572 AIR74898 AJG00885 AJG00886 AJG00887 AJG00888 AJG00889 AJG00890 AJG00892 AJG00893 AJQ81029 AJT55533 AJT55534 AJT55536 AJT55540 BAA36694 BAA36696 CAB09726 CAB10169 CAB10588 CAC51514 CAC81665 CAD29850 CAD43297 CAG17775 CAI30430 CAJ26347 CAJ27264 CAJ58683 CAJ58684 CAJ75454 CAJ75455 CAJ75456 CAJ98536 CAL29650 CAL29651 CAL29652 CAL29654 CAL29655 CAL44958 CAL81554 CAM88659 CAP12642 CAP18774 CAQ55544 CAQ63558 CAS02274 CAS02276 CAS02277 CAS02278 CAS02280 CAS02281 CAT05639 CBG76068 CBG76069 CBS91666 CBX23453 CCC42284 CCI71884 CCI71885 CDK60403 CDX09879 CED80062 CEJ95762 CEK43031 EAW95162 EAW95163 EAW95164 EAW95165 EAW95166 EAW95167 P18577 AB018644 BAA33927 AB018645 BAA33928 AB030388 BAA82627 AB049753 BAB16597 AF056965 AAC18092 AF510065 AAN75121 AF510066 AAN75122 AF510067 AAN75123 AF510068 AAN75124 AM295498 CAL29648 AM295506 CAL29656 AY603478 AAT35811 BC075081 AAH75081 BC139905 AAI39906 BM684087 DQ178642 ABA25912 DQ266353 ABB97471 DQ266400 ABB69097 DQ322275 ABC55358 FR691748 CBX20979 FR691749 CBX20980 FR691750 CBX20981 GU474431 ADB95952 GU563377 ADD62791 GU810838 ADE44507 HE572747 CCC42283 HG326207 CDG06148 HQ711843 ADU25347 HQ711844 ADU25348 HQ711845 ADU25349 HQ711846 ADU25350 HQ711847 ADU25351 JF436968 AEK48079 JX420291 AFS64571 JX420292 AFS64572 JX420293 AFS64573 JX420294 AFS64574 JX420295 AFS64575 JX420296 AFS64576 JX420297 AFS64577 JX420298 AFS64578 JX420299 AFS64579 JX420300 AFS64580 JX420301 AFS64581 JX420302 AFS64582 KF515558 AGZ16435 KM975480 AJG00891 KP056313 AJO62142 M34015 AAA36567 S57967 AAB26080 X54534 CAA38401 X63095 CAA44809 X63096 CAA44810 X63098 CAA44812 XM_005245957 XP_005246014 XM_006710810 XP_006710873 XM_011541888 XP_011540190 XM_011541889 XP_011540191 XM_011541890 XP_011540192 XM_011541891 XP_011540193 NM_020485 NP_065231 NM_138616 NP_619522 NM_138617 NP_619523 NM_138618 NP_619524 |
Function | May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Restricted to tissues or cell lines expressing erythroid characters. Isoform 4g and isoform RhPI-Alpha are expressed in immature erythroblasts but not in mature erythroblasts. {ECO:0000269|PubMed:8117271}. |
RhCE CRISPR/Cas9 KO Plasmid (h) - sc-409476 from Santa Cruz Biotechnology
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RhCE HDR Plasmid (h) - sc-409476-HDR from Santa Cruz Biotechnology
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RhCE Double Nickase Plasmid (h) - sc-409476-NIC from Santa Cruz Biotechnology
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RhCE Double Nickase Plasmid (h2) - sc-409476-NIC-2 from Santa Cruz Biotechnology
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RhD/CE CRISPR Activation Plasmid (h) - sc-409476-ACT from Santa Cruz Biotechnology
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RhCE CRISPR Activation Plasmid (h2) - sc-409476-ACT-2 from Santa Cruz Biotechnology
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RhCE Lentiviral Activation Particles (h) - sc-409476-LAC from Santa Cruz Biotechnology
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RhCE Lentiviral Activation Particles (h2) - sc-409476-LAC-2 from Santa Cruz Biotechnology
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RhC siRNA (h) - sc-72146 from Santa Cruz Biotechnology
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RhC shRNA Plasmid (h) - sc-72146-SH from Santa Cruz Biotechnology
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RhC shRNA (h) Lentiviral Particles - sc-72146-V from Santa Cruz Biotechnology
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RHCE RNAi - H00006006-R03 from Novus Biologicals
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RHCE RNAi - H00006006-R04 from Novus Biologicals
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RHCE RNAi - H00006006-R01 from Novus Biologicals
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MISSION® esiRNA - EHU115741 from Sigma-Aldrich
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MISSION® esiRNA - EHU116391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2459 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2459 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03786 from Sigma-Aldrich
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RHCE siRNA (Human) - CRH4074 from Cohesion Biosciences
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RHCE RNAi - H00006006-R02 from Novus Biologicals
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RHCE - MBS8207186 from MyBioSource
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Human RHCE siRNA - orb264576 from Biorbyt
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RHCE shRNA Plasmid (Human) - CHH4074 from Cohesion Biosciences
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RHCE miRNA 3'UTR clone - MiUTR3H-00267 from Creative biogene
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