Gene Symbol | KCNH4 |
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Entrez Gene | 23415 |
Alt Symbol | BEC2, ELK1, Kv12.3 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated eag related subfamily H, member 4 |
Other Description | ELK channel 1|brain-specific eag-like channel 2|ether-a-go-go K(+) channel family member|ether-a-go-go-like potassium channel 1|potassium voltage-gated channel subfamily H member 4|potassium voltage-gated channel, subfamily H (eag-related), member 4|voltage-gated potassium channel subunit Kv12.3 |
Swissprots | Q9UQ05 |
Accessions | EAW60809 Q9UQ05 AB022698 BAA83592 AW084816 BC140292 AAI40293 NM_012285 NP_036417 |
Function | Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits an outward current, but shows no inactivation. Channel properties may be modulated by cAMP and subunit assembly. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Detected only in brain, in particular in the telencephalon. Detected in putamen and caudate nucleus, and at lower levels in cerebral cortex, occipital and hippocampus. |
KCNH4 CRISPR/Cas9 KO Plasmid (h) - sc-411736 from Santa Cruz Biotechnology
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KCNH4 HDR Plasmid (h) - sc-411736-HDR from Santa Cruz Biotechnology
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KCNH4 Double Nickase Plasmid (h) - sc-411736-NIC from Santa Cruz Biotechnology
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KCNH4 Double Nickase Plasmid (h2) - sc-411736-NIC-2 from Santa Cruz Biotechnology
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KCNH4 CRISPR Activation Plasmid (h) - sc-411736-ACT from Santa Cruz Biotechnology
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KCNH4 CRISPR Activation Plasmid (h2) - sc-411736-ACT-2 from Santa Cruz Biotechnology
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KCNH4 Lentiviral Activation Particles (h) - sc-411736-LAC from Santa Cruz Biotechnology
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KCNH4 Lentiviral Activation Particles (h2) - sc-411736-LAC-2 from Santa Cruz Biotechnology
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KCNH4 siRNA (h) - sc-93952 from Santa Cruz Biotechnology
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KCNH4 shRNA Plasmid (h) - sc-93952-SH from Santa Cruz Biotechnology
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KCNH4 shRNA (h) Lentiviral Particles - sc-93952-V from Santa Cruz Biotechnology
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Kv12.3 RNAi - H00023415-R03 from Novus Biologicals
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MISSION® esiRNA - EHU057621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10944 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10944 from Sigma-Aldrich
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KCNH4 siRNA (Human) - CRH8254 from Cohesion Biosciences
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KCNH4, siRNA - MBS8239202 from MyBioSource
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shRNA set against Human KCNH4 (NM_012285.2) - SHH323071 from Creative biogene
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KCNH4 shRNA Plasmid (Human) - CHH8254 from Cohesion Biosciences
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KCNH4 miRNA 3'UTR clone - MiUTR3H-06890 from Creative biogene
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