| Gene Symbol | CLDN10 |
|---|---|
| Entrez Gene | 506545 |
| Alt Symbol | - |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | claudin 10 |
| Other Description | claudin-10 |
| Swissprots | A7Z072 Q5E9L0 |
| Accessions | DAA23768 DAA23769 Q5E9L0 BC153270 AAI53271 BT020910 AAX08927 NM_001014857 NP_001014857 NM_001105609 NP_001099079 |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. May form permselective paracellular pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. Plays a key role in controlling cation selectivity and transport in the thick ascending limb (TAL) of Henle's loop in kidney (By similarity). {ECO:0000250}. |
| Subcellular Location | Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | Tight junction, Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Hepatitis C |
Claudin-10 (CLDN10), Recombinant Protein - MBS7011551 from MyBioSource
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