| Gene Symbol | GOT1 |
|---|---|
| Entrez Gene | 100340431 |
| Alt Symbol | - |
| Species | Rabbit |
| Gene Type | protein-coding |
| Description | glutamic-oxaloacetic transaminase 1, soluble |
| Other Description | aspartate aminotransferase 1|glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) |
| Swissprots | P12343 |
| Accessions | GBCN01004027 XM_002718630 XP_002718676 |
| Function | Biosynthesis of L-glutamate from L-aspartate or L- cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3- mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain (By similarity). {ECO:0000250}. |
| Subcellular Location | Cytoplasm. |
| Top Pathways | Cysteine and methionine metabolism, Tyrosine metabolism, 2-Oxocarboxylic acid metabolism, Carbon metabolism, Biosynthesis of amino acids |
Aspartate aminotransferase, cytoplasmic, GOT1, Rabbit, ELISA Kit - E1214Rb from ARP American Research Products
|
||||||||||
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) , ELISA Kit - MBS704087 from MyBioSource
|
||||||||||
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) , ELISA Kit - MBS9310870 from MyBioSource
|
||||||||||
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) , ELISA Kit - MBS9342189 from MyBioSource
|
||||||||||
Rabbit GOT1 ELISA Kit - E074202 from Biobool
|