Gene Symbol | SPAG8 |
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Entrez Gene | 26206 |
Alt Symbol | BS-84, CILD28, CT142, HSD-1, SMP1, SPAG3, hSMP-1 |
Species | Human |
Gene Type | protein-coding |
Description | sperm associated antigen 8 |
Other Description | sperm membrane protein 1|sperm membrane protein BS-84|sperm-associated antigen 8 |
Swissprots | Q8WWB4 E9PDV6 Q5TCV8 B4DY89 Q99932 Q12937 |
Accessions | EAW58335 EAW58336 Q99932 AI028727 AK302313 BAG63651 BC019247 AAH19247 BI757195 CA314354 DQ890798 ABM81724 EU176503 ABW03304 S83157 AAB46833 U12978 AAA21129 XM_005251436 XP_005251493 XM_005251437 XP_005251494 XM_005251438 XP_005251495 XM_011517844 XP_011516146 NM_001039592 NP_001034681 NM_172312 NP_758516 NM_012436 |
Function | May play a role in fertility and microtubule formation through interaction with RANBP9. {ECO:0000269|PubMed:10500252}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000269|PubMed:15014887, ECO:0000269|PubMed:8788182}. Note=Acrosomal region of the head of mature sperm cells. |
Tissue Specificity | Expressed in testis (germ cells), but not in liver, kidney, prostate and small intestine. {ECO:0000269|PubMed:8788182}. |
SPAG8 CRISPR/Cas9 KO Plasmid (h) - sc-411896 from Santa Cruz Biotechnology
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SPAG8 HDR Plasmid (h) - sc-411896-HDR from Santa Cruz Biotechnology
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SPAG8 Double Nickase Plasmid (h) - sc-411896-NIC from Santa Cruz Biotechnology
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SPAG8 Double Nickase Plasmid (h2) - sc-411896-NIC-2 from Santa Cruz Biotechnology
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SPAG8 CRISPR Activation Plasmid (h) - sc-411896-ACT from Santa Cruz Biotechnology
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SPAG8 CRISPR Activation Plasmid (h2) - sc-411896-ACT-2 from Santa Cruz Biotechnology
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SPAG8 Lentiviral Activation Particles (h) - sc-411896-LAC from Santa Cruz Biotechnology
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SPAG8 Lentiviral Activation Particles (h2) - sc-411896-LAC-2 from Santa Cruz Biotechnology
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SPAG8 siRNA (h) - sc-92788 from Santa Cruz Biotechnology
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SPAG8 shRNA Plasmid (h) - sc-92788-SH from Santa Cruz Biotechnology
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SPAG8 shRNA (h) Lentiviral Particles - sc-92788-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU067481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20391 from Sigma-Aldrich
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SPAG8 siRNA (Human) - CRH8755 from Cohesion Biosciences
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SPAG8 - MBS8202874 from MyBioSource
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shRNA set against Human SPAG8 (NM_172312.1) - SHH415888 from Creative biogene
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shRNA set against Human SPAG8(NM_172312.1) - SHL025884 from Creative biogene
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shRNA set against Human SPAG8(NM_001039592.1) - SHL025948 from Creative biogene
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Human SPAG8 siRNA - orb269257 from Biorbyt
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SPAG8 shRNA Plasmid (Human) - CHH8755 from Cohesion Biosciences
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SPAG8 miRNA 3'UTR clone - MiUTR1H-09798 from Creative biogene
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SPAG8 miRNA 3'UTR clone - MiUTR1H-09799 from Creative biogene
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