Gene Symbol |
LIG1
|
Entrez Gene |
3978
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ligase I, DNA, ATP-dependent
|
Other Description |
DNA ligase 1|polydeoxyribonucleotide synthase [ATP] 1
|
Swissprots |
Q2TB12 P18858 B2RAI8 Q32P23 B4DTU4
|
Accessions |
AAM77697 BAC81763 EAW52316 EAW52317 P18858 AB208791 BAD92028 AK225863 AK297296 BAG59764 AK300370 BAG62106 AK300607 BAG62303 AK303644 BAG64647 AK314210 BAG36885 BC108318 AAI08319 BC110622 AAI10623 M36067 AAA59518 XM_005258934 XP_005258991 XM_006723215 XP_006723278 XM_006723216 XP_006723279 XR_243932 XR_430200 NM_000234 NP_000225 NM_001289063 NP_001275992 NM_001289064 NP_001275993 NR_110296
|
Function |
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
|
Subcellular Location |
Nucleus.
|
Top Pathways |
DNA replication, Mismatch repair, Base excision repair, Nucleotide excision repair
|