Gene Symbol | BRINP3 |
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Entrez Gene | 339479 |
Alt Symbol | DBCCR1L, DBCCR1L1, FAM5C |
Species | Human |
Gene Type | protein-coding |
Description | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
Other Description | BMP/retinoic acid-inducible neural-specific protein 3|DBCCR1-like protein 1|family with sequence similarity 5, member C|protein FAM5C |
Swissprots | O95726 Q2M330 B3KVP1 Q76B58 B7Z260 |
Accessions | EAW91222 Q76B58 AB111893 BAD04066 AK123024 BAG53853 AK123637 BAG53928 AK294365 BAH11746 BC105052 AAI05053 BC105054 AAI05055 U67037 AAD09521 XM_005245117 XP_005245174 XM_005245118 XP_005245175 XM_005245120 XP_005245177 XM_011509472 XP_011507774 XM_011509473 XP_011507775 XM_011509474 XP_011507776 XM_011509475 XP_011507777 XM_011509476 XP_011507778 NM_199051 NP_950252 |
Function | Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development. {ECO:0000269|PubMed:17138656}. |
Subcellular Location | Secreted {ECO:0000305}. Mitochondrion {ECO:0000250}. |
Tissue Specificity | Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues. {ECO:0000269|PubMed:17138656, ECO:0000269|PubMed:18430236, ECO:0000269|PubMed:19787213}. |
BRINP3 (N-16) - sc-139453 from Santa Cruz Biotechnology
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BRINP3 (D-16) - sc-139455 from Santa Cruz Biotechnology
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Anti-FAM5C antibody - ab102807 from Abcam
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Anti-BRINP3 / FAM5C Antibody (aa47-76, AP) - LS-C257015 from LifeSpan Bioscience
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Anti-BRINP3 / FAM5C Antibody (aa47-76, APC) - LS-C257016 from LifeSpan Bioscience
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Anti-BRINP3 / FAM5C Antibody (aa47-76, FITC) - LS-C257018 from LifeSpan Bioscience
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Anti-BRINP3 / FAM5C Antibody (aa47-76, Azide-free, HRP) - LS-C257019 from LifeSpan Bioscience
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Anti-BRINP3 / FAM5C Antibody (aa47-76, Biotin) - LS-C257017 from LifeSpan Bioscience
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Anti-BRINP3 / FAM5C Antibody (aa47-76) - LS-C329536 from LifeSpan Bioscience
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Anti-BRINP3 / FAM5C Antibody (aa47-76, PE) - LS-C257020 from LifeSpan Bioscience
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Anti-BRINP3 / FAM5C Antibody (aa40-68) - LS-C166016 from LifeSpan Bioscience
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FAM5C Antibody - NBP2-31581 from Novus Biologicals
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ANTI-FAM5C (N-TERM) antibody produced in rabbit - SAB1301960 from Sigma-Aldrich
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Anti-FAM5C antibody produced in rabbit - HPA054693 from Sigma-Aldrich
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FAM5C-Antibody-N-term - AP9487a from Abgent, a WuXi AppTec company
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FAM5C Antibody - N-terminal region (OAAB06084) - OAAB06084 from Aviva Systems Biology
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Anti -FAM5C, NT (FAM5C, DBCCR1L, DBCCR1L1, Protein FAM5C, DBCCR1-like protein 1) - 035468 from USBiological Life Science
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Anti -FAM5C, NT (FAM5C, DBCCR1L, DBCCR1L1, Protein FAM5C, DBCCR1-like protein 1) (AP) - 035468-AP from USBiological Life Science
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Anti -FAM5C, NT (FAM5C, DBCCR1L, DBCCR1L1, Protein FAM5C, DBCCR1-like protein 1) (APC) - 035468-APC from USBiological Life Science
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Anti -FAM5C, NT (FAM5C, DBCCR1L, DBCCR1L1, Protein FAM5C, DBCCR1-like protein 1) (Azidefree) (HRP) - 035468-HRP from USBiological Life Science
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Anti -FAM5C, NT (FAM5C, DBCCR1L, DBCCR1L1, Protein FAM5C, DBCCR1-like protein 1) (Biotin) - 035468-Biotin from USBiological Life Science
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Anti -FAM5C, NT (FAM5C, DBCCR1L, DBCCR1L1, Protein FAM5C, DBCCR1-like protein 1) (FITC) - 035468-FITC from USBiological Life Science
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Anti -FAM5C, NT (FAM5C, DBCCR1L, DBCCR1L1, Protein FAM5C, DBCCR1-like protein 1) (PE) - 035468-PE from USBiological Life Science
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FAM5C antibody (FITC) - orb187929 from Biorbyt
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FAM5C (N-term) antibody - AP51586PU-N from Acris Antibodies
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