Gene Symbol | DUSP11 |
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Entrez Gene | 8446 |
Alt Symbol | PIR1 |
Species | Human |
Gene Type | protein-coding |
Description | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) |
Other Description | RNA/RNP complex-1-interacting phosphatase|RNA/RNP complex-interacting phosphatase|dual specificity protein phosphatase 11|phosphatase that interacts with RNA/RNP complex 1|serine/threonine specific protein phosphatase |
Swissprots | Q6AI47 O75319 B2RCT8 Q9BWE3 |
Accessions | EAW99718 EAW99719 O75319 AF023917 AAC39925 AK315271 BAG37685 BC000346 AAH00346 BP349009 BP359552 CR627368 CAH10467 DQ891356 ABM82282 DQ894537 ABM85463 XR_244962 NM_003584 NP_003575 |
Function | Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. In addition, has phosphatase activity with ATP, ADP and O-methylfluorescein phosphate (in vitro). Binds to RNA. May participate in nuclear mRNA metabolism. {ECO:0000269|PubMed:10347225, ECO:0000269|PubMed:24447265, ECO:0000269|PubMed:9685386}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9685386}. Nucleus speckle {ECO:0000269|PubMed:9685386}. |
PIR1 CRISPR/Cas9 KO Plasmid (h) - sc-408162 from Santa Cruz Biotechnology
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PIR1 HDR Plasmid (h) - sc-408162-HDR from Santa Cruz Biotechnology
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PIR1 Double Nickase Plasmid (h) - sc-408162-NIC from Santa Cruz Biotechnology
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PIR1 Double Nickase Plasmid (h2) - sc-408162-NIC-2 from Santa Cruz Biotechnology
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PIR1 CRISPR Activation Plasmid (h) - sc-408162-ACT from Santa Cruz Biotechnology
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PIR1 CRISPR Activation Plasmid (h2) - sc-408162-ACT-2 from Santa Cruz Biotechnology
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PIR1 Lentiviral Activation Particles (h) - sc-408162-LAC from Santa Cruz Biotechnology
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PIR1 Lentiviral Activation Particles (h2) - sc-408162-LAC-2 from Santa Cruz Biotechnology
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PIR1 siRNA (h) - sc-61357 from Santa Cruz Biotechnology
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PIR1 shRNA Plasmid (h) - sc-61357-SH from Santa Cruz Biotechnology
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PIR1 shRNA (h) Lentiviral Particles - sc-61357-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU011281 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0095 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0094 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0096 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7543 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7543 from Sigma-Aldrich
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DUSP11 siRNA (Human) - CRH5534 from Cohesion Biosciences
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DUSP11 RNAi - H00008446-R02 from Novus Biologicals
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DUSP11 - MBS8207518 from MyBioSource
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shRNA set against Human DUSP11 (NM_003584.2) - SHH281685 from Creative biogene
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DUSP11 shRNA Plasmid (Human) - CHH5534 from Cohesion Biosciences
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DUSP11 miRNA 3'UTR clone - MiUTR3H-05658 from Creative biogene
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