| Gene Symbol |
IGFBP5
|
| Entrez Gene |
3488
|
| Alt Symbol |
IBP5
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
insulin-like growth factor binding protein 5
|
| Other Description |
IBP-5|IGF-binding protein 5|IGFBP-5|insulin-like growth factor-binding protein 5
|
| Swissprots |
Q5U0A3 P24593
|
| Accessions |
AAA72051 AAS16353 AAY14662 CAJ21553 CCA64016 CCA64017 CCA64018 CCA64019 EAW70574 EAW70575 P24593 AF055033 AAC09368 AF147308 AK314992 BAG37488 AU132181 AV710460 BC008099 AAH08099 BC011453 AAH11453 BC018427 AAH18427 BC032366 BC039838 BC046102 BC073984 BC089383 BE795293 BM920595 BQ717583 BQ940805 BT019706 AAV38512 BT019707 AAV38513 CD679409 CR456809 CAG33090 DA691367 L27560 M62782 AAA53505 M65062 AAD04730 R71383 NM_000599 NP_000590
|
| Function |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Osteosarcoma, and at lower levels in liver, kidney and brain.
|
![Western Blot: IGFBP5 Overexpression Lysate (Adult Normal) [NBL1-11875] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IGFBP5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4602_IGFBP5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-11875-img0002.jpg)