Gene Symbol | TIPARP |
---|---|
Entrez Gene | 25976 |
Alt Symbol | ARTD14, PARP7, pART14 |
Species | Human |
Gene Type | protein-coding |
Description | TCDD-inducible poly(ADP-ribose) polymerase |
Other Description | ADP-ribosyltransferase diphtheria toxin-like 14|TCDD-inducible poly [ADP-ribose] polymerase|poly [ADP-ribose] polymerase 7 |
Swissprots | D3DNK6 Q86VP4 Q68CY9 Q7Z3E1 Q9Y4P7 |
Accessions | EAW78725 EAW78726 EAW78727 EAW78728 Q7Z3E1 AK097785 AK291261 BAF83950 AL080156 CAB45747 AM393433 CAL38311 BC034397 AAH34397 BC050350 AAH50350 BX537965 CAD97929 CR749647 CAH18441 DB033700 XM_011512668 XP_011510970 XM_011512669 XP_011510971 NM_001184717 NP_001171646 NM_001184718 NP_001171647 NM_015508 NP_056323 |
Function | Poly [ADP-ribose] polymerase using NAD(+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptive response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals (By similarity). {ECO:0000250}. |