| Gene Symbol |
ATRAID
|
| Entrez Gene |
51374
|
| Alt Symbol |
APR--3, APR-3, APR3, C2orf28, HSPC013, PRO240, p18
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
all-trans retinoic acid-induced differentiation factor
|
| Other Description |
apoptosis related protein 3|apoptosis related protein APR-3|apoptosis-related protein 3
|
| Swissprots |
A8K779 A8C1S2 Q9Y5L7 Q96FF6 Q6UW56 Q96RT2 Q9Y2R7
|
| Accessions |
AAX93173 EAX00615 EAX00616 EAX00617 EAX00618 EAX00619 Q6UW56 AA604432 AB009017 BAF80618 AF077037 AAD27770 AF144055 AAD31317 AF275744 AAK69412 AK291894 BAF84583 AW966996 AY358968 AAQ89327 BC002846 AAH02846 BC011006 AAH11006 BC021237 AAH21237 BC035850 AAH35850 BI194121 BQ420456 BQ718371 BQ962996 CA450289 CD513162 CF126865 NM_001170795 NP_001164266 NM_016085 NP_057169 NM_080592 NP_542159
|
| Function |
Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. {ECO:0000269|PubMed:21723284}.
|
| Subcellular Location |
Nucleus envelope. Cell membrane; Single-pass membrane protein. Note=Colocalizes with NELL1 on the nuclear envelope and the perinuclear region.
|
| Tissue Specificity |
Weakly expressed in hematopoietic cell lines. {ECO:0000269|PubMed:11042152}.
|
![Western Blot: APR3 Overexpression Lysate (Adult Normal) [NBL1-08407] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for APR3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1830_APR3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08407-img0002.jpg)