Gene Symbol |
CLUAP1
|
Entrez Gene |
23059
|
Alt Symbol |
CFAP22, FAP22
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
clusterin associated protein 1
|
Other Description |
cilia and flagella associated protein 22|clusterin-associated protein 1|flagellar associated protein 22, qilin-like protein, homolog|qilin
|
Swissprots |
Q9H8T1 Q9H8R4 Q65ZA3 Q96AJ1 O75138
|
Accessions |
EAW85352 EAW85353 EAW85354 Q96AJ1 AB014543 BAA31618 AB089691 BAD44779 AK023319 BAB14523 AK023359 BAB14542 AK294318 BAG57592 BC017070 AAH17070 BQ446386 DA502615 T49451 XM_006720867 XP_006720930 NM_015041 NP_055856 NM_024793 NP_079069
|
Function |
Required for cilia biogenesis. Appears to function within the multiple intraflagellar transport complex B (IFT-B). Key regulator of hedgehog signaling (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus. Cell projection, cilium.
|
Tissue Specificity |
Expressed in testis, thyroid and trachea and to a lower extent in spinal cord and adrenal gland. Highly expressed in colon cancer and osteosarcoma cell lines. {ECO:0000269|PubMed:15480429, ECO:0000269|PubMed:17203229}.
|