Gene Symbol | GUCY1A2 |
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Entrez Gene | 2977 |
Alt Symbol | GC-SA2, GUC1A2 |
Species | Human |
Gene Type | protein-coding |
Description | guanylate cyclase 1, soluble, alpha 2 |
Other Description | GCS-alpha-2|guanylate cyclase soluble subunit alpha-2 |
Swissprots | A1L4C4 B7ZLT5 P33402 |
Accessions | EAW67081 P33402 AK001875 AK022090 AK025115 AK098142 BC036599 BC047463 BC130484 AAI30485 BC130488 AAI30489 BC144033 AAI44034 CA774108 X63282 CAA44921 Z50053 CAA90393 NM_000855 NP_000846 NM_001256424 NP_001243353 |
Function | Has guanylyl cyclase on binding to the beta-1 subunit. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Isoform 1 is expressed in fetal brain, liver, colon, endothelium and testis. Isoform 2 is expressed only in liver, colon and endothelium. |
Top Pathways | Salivary secretion, cGMP-PKG signaling pathway, Oxytocin signaling pathway, Circadian entrainment, Vascular smooth muscle contraction |
GCS-α-2 CRISPR/Cas9 KO Plasmid (h) - sc-404305 from Santa Cruz Biotechnology
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GCS-α-2 HDR Plasmid (h) - sc-404305-HDR from Santa Cruz Biotechnology
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GCS-α-2 Double Nickase Plasmid (h) - sc-404305-NIC from Santa Cruz Biotechnology
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GCS-α-2 Double Nickase Plasmid (h2) - sc-404305-NIC-2 from Santa Cruz Biotechnology
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GCS-α-2 CRISPR Activation Plasmid (h) - sc-404305-ACT from Santa Cruz Biotechnology
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GCS-α-2 CRISPR Activation Plasmid (h2) - sc-404305-ACT-2 from Santa Cruz Biotechnology
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GCS-α-2 Lentiviral Activation Particles (h) - sc-404305-LAC from Santa Cruz Biotechnology
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GCS-α-2 Lentiviral Activation Particles (h2) - sc-404305-LAC-2 from Santa Cruz Biotechnology
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GCS-α-2 siRNA (h) - sc-41012 from Santa Cruz Biotechnology
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GCS-α-2 shRNA Plasmid (h) - sc-41012-SH from Santa Cruz Biotechnology
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GCS-α-2 shRNA (h) Lentiviral Particles - sc-41012-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU081191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9798 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9798 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03714 from Sigma-Aldrich
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GUCY1A2 siRNA (Human) - CRH2016 from Cohesion Biosciences
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Guanylyl Cyclase alpha 2 RNAi - H00002977-R01 from Novus Biologicals
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GUCY1A2 - MBS8233789 from MyBioSource
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shRNA set against Human GUCY1A2 (NM_000855.2) - SHH309322 from Creative biogene
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Human GUCY1A2 siRNA - orb262518 from Biorbyt
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GUCY1A2 shRNA Plasmid (Human) - CHH2016 from Cohesion Biosciences
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GUCY1A2 miRNA 3'UTR clone - MiUTR3H-03980 from Creative biogene
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