| Gene Symbol |
CGGBP1
|
| Entrez Gene |
8545
|
| Alt Symbol |
CGGBP, p20-CGGBP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CGG triplet repeat binding protein 1
|
| Other Description |
20 kDa CGG-binding protein|CGG triplet repeat-binding protein 1|CGG-binding protein 1|p20-CGG binding protein|p20-CGGBP DNA-binding protein
|
| Swissprots |
O15183 Q9UFW8 D3DU38
|
| Accessions |
AAD04161 EAW68863 EAW68864 Q9UFW8 AJ000258 CAA03974 AL117392 CAB55894 AL357195 AM393707 CAL38583 BC005222 BC042194 BC052980 AAH52980 BE501563 BU537042 CR456854 CAG33135 XM_011534170 XP_011532472 NM_001008390 NP_001008391 NM_001195308 NP_001182237 NM_003663 NP_003654
|
| Function |
Binds to nonmethylated 5'-d(CGG)(n)-3' trinucleotide repeats in the FMR1 promoter. May play a role in regulating FMR1 promoter. {ECO:0000269|PubMed:9201980}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:9201980}.
|
| Tissue Specificity |
Ubiquitous. Highly expressed in placenta, thymus, lymph nodes, cerebellum and cerebral cortex. Low expression in other regions of the brain. {ECO:0000269|PubMed:14667814}.
|
![Western Blot: CGGBP1 Overexpression Lysate (Adult Normal) [NBL1-09134] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CGGBP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6280_CGGBP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09134-img0002.jpg)
![Western Blot: CGGBP1 Overexpression Lysate (Adult Normal) [NBP2-08807] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CGGBP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5654_CGGBP1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-08807-img0001.jpg)