| Gene Symbol |
mrcB
|
| Entrez Gene |
944843
|
| Alt Symbol |
ECK0148, JW0145, pbpF, ponB
|
| Species |
Escherichia coli
|
| Gene Type |
protein-coding
|
| Description |
fused glycosyl transferase and transpeptidase
|
| Other Description |
-
|
| Swissprots |
P75664 P02919
|
| Accessions |
AAC73260 NP_414691
|
| Function |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
|
| Subcellular Location |
Cell inner membrane; Single-pass type II membrane protein.
|
| Top Pathways |
Peptidoglycan biosynthesis
|