Gene Symbol | MOAP1 |
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Entrez Gene | 64112 |
Alt Symbol | MAP-1, PNMA4 |
Species | Human |
Gene Type | protein-coding |
Description | modulator of apoptosis 1 |
Other Description | MAP1|paraneoplastic Ma antigen family member 4|paraneoplastic antigen Ma4|paraneoplastic antigen like 4 |
Swissprots | Q9HAS1 Q96BY2 Q9H833 B2RDF6 |
Accessions | EAW81516 Q96BY2 AF305550 AAG31786 AK024029 BAB14788 AK315522 BAG37903 AM392976 CAL37854 BC015044 AAH15044 BG475323 BG699993 BG704865 DQ891177 ABM82103 DQ894359 ABM85285 NM_022151 NP_071434 |
Function | Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. {ECO:0000269|PubMed:15949439}. |
Tissue Specificity | Widely expressed, with high levels in heart and brain. {ECO:0000269|PubMed:19366867}. |
MOAP1 CRISPR/Cas9 KO Plasmid (h) - sc-408271 from Santa Cruz Biotechnology
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MOAP1 HDR Plasmid (h) - sc-408271-HDR from Santa Cruz Biotechnology
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MOAP1 Double Nickase Plasmid (h) - sc-408271-NIC from Santa Cruz Biotechnology
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MOAP1 Double Nickase Plasmid (h2) - sc-408271-NIC-2 from Santa Cruz Biotechnology
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MOAP1 CRISPR Activation Plasmid (h) - sc-408271-ACT from Santa Cruz Biotechnology
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MOAP1 CRISPR Activation Plasmid (h2) - sc-408271-ACT-2 from Santa Cruz Biotechnology
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MOAP1 Lentiviral Activation Particles (h) - sc-408271-LAC from Santa Cruz Biotechnology
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MOAP1 Lentiviral Activation Particles (h2) - sc-408271-LAC-2 from Santa Cruz Biotechnology
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MOAP1 siRNA (h) - sc-62629 from Santa Cruz Biotechnology
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MOAP1 shRNA Plasmid (h) - sc-62629-SH from Santa Cruz Biotechnology
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MOAP1 shRNA (h) Lentiviral Particles - sc-62629-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU036801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14450 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14450 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08326 from Sigma-Aldrich
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MOAP1 siRNA (Human) - CRJ1928 from Cohesion Biosciences
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MAP1 RNAi - H00064112-R01 from Novus Biologicals
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shRNA set against Human MOAP1 (NM_022151.4) - SHH343260 from Creative biogene
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shRNA set against Human MOAP1(NM_022151.4) - SHH194717 from Creative biogene
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Human MOAP1 siRNA - orb272429 from Biorbyt
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MOAP1 shRNA Plasmid (Human) - CHJ1928 from Cohesion Biosciences
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MOAP1 miRNA 3'UTR clone - MiUTR1H-06368 from Creative biogene
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