Gene Symbol |
MTFP1
|
Entrez Gene |
51537
|
Alt Symbol |
HSPC242, MTP18
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
mitochondrial fission process 1
|
Other Description |
mitochondrial 18 kDa protein|mitochondrial fission process protein 1|mitochondrial fission protein MTP18|mitochondrial protein 18 kDa
|
Swissprots |
Q9P0N6 Q9H3K1 Q9UDX5 A6NFQ5
|
Accessions |
AAF19257 CAJ42782 CCO13775 EAW59889 EAW59890 EAW59891 Q9UDX5 AF060924 AAG43136 AF151076 AAF36162 AK026104 BC001608 AAH01608 BC009300 AAH09300 BC014446 AAH14446 BC030989 AAH30989 BC038831 AAH38831 BC046132 AAH46132 BQ187590 CB107806 CB142469 CR456345 CAG30231 NM_001003704 NP_001003704 NM_016498 NP_057582
|
Function |
Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis. {ECO:0000269|PubMed:15155745, ECO:0000269|PubMed:15985469}.
|
Subcellular Location |
Mitochondrion inner membrane {ECO:0000305|PubMed:15155745, ECO:0000305|PubMed:15985469}; Multi- pass membrane protein {ECO:0000305|PubMed:15155745, ECO:0000305|PubMed:15985469}.
|