MTFP1

Gene Symbol MTFP1
Entrez Gene 51537
Alt Symbol HSPC242, MTP18
Species Human
Gene Type protein-coding
Description mitochondrial fission process 1
Other Description mitochondrial 18 kDa protein|mitochondrial fission process protein 1|mitochondrial fission protein MTP18|mitochondrial protein 18 kDa
Swissprots Q9P0N6 Q9H3K1 Q9UDX5 A6NFQ5
Accessions AAF19257 CAJ42782 CCO13775 EAW59889 EAW59890 EAW59891 Q9UDX5 AF060924 AAG43136 AF151076 AAF36162 AK026104 BC001608 AAH01608 BC009300 AAH09300 BC014446 AAH14446 BC030989 AAH30989 BC038831 AAH38831 BC046132 AAH46132 BQ187590 CB107806 CB142469 CR456345 CAG30231 NM_001003704 NP_001003704 NM_016498 NP_057582
Function Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis. {ECO:0000269|PubMed:15155745, ECO:0000269|PubMed:15985469}.
Subcellular Location Mitochondrion inner membrane {ECO:0000305|PubMed:15155745, ECO:0000305|PubMed:15985469}; Multi- pass membrane protein {ECO:0000305|PubMed:15155745, ECO:0000305|PubMed:15985469}.

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