Gene Symbol | RBM3 |
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Entrez Gene | 5935 |
Alt Symbol | IS1-RNPL, RNPL |
Species | Human |
Gene Type | protein-coding |
Description | RNA binding motif (RNP1, RRM) protein 3 |
Other Description | RNA-binding motif protein 3|RNA-binding protein 3|putative RNA-binding protein 3 |
Swissprots | P98179 |
Accessions | CBB98488 EAW50765 EAW50766 EAW50767 EAW50768 P98179 AA460548 AK000859 AK026664 BAB15519 AK289614 BAF82303 AK309137 AY203954 AAP34477 BC006825 AAH06825 BI523929 BQ429805 BX647914 CD559009 XM_011543938 XP_011542240 XM_011543939 XP_011542241 NM_006743 NP_006734 NM_001017430 NM_001017431 |
Function | Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=Localizes in mRNA granules in dentrites. {ECO:0000250}. |
RBM3 CRISPR/Cas9 KO Plasmid (h) - sc-406296 from Santa Cruz Biotechnology
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RBM3 HDR Plasmid (h) - sc-406296-HDR from Santa Cruz Biotechnology
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RBM3 Double Nickase Plasmid (h) - sc-406296-NIC from Santa Cruz Biotechnology
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RBM3 Double Nickase Plasmid (h2) - sc-406296-NIC-2 from Santa Cruz Biotechnology
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RBM3 CRISPR Activation Plasmid (h) - sc-406296-ACT from Santa Cruz Biotechnology
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RBM3 CRISPR Activation Plasmid (h2) - sc-406296-ACT-2 from Santa Cruz Biotechnology
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RBM3 Lentiviral Activation Particles (h) - sc-406296-LAC from Santa Cruz Biotechnology
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RBM3 Lentiviral Activation Particles (h2) - sc-406296-LAC-2 from Santa Cruz Biotechnology
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RBM3 siRNA (h) - sc-91221 from Santa Cruz Biotechnology
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RBM3 shRNA Plasmid (h) - sc-91221-SH from Santa Cruz Biotechnology
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RBM3 shRNA (h) Lentiviral Particles - sc-91221-V from Santa Cruz Biotechnology
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RBM3 RNAi - H00005935-R01 from Novus Biologicals
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RBM3 RNAi - H00005935-R03 from Novus Biologicals
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MISSION® esiRNA - EHU133121 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18040 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18040 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12394 from Sigma-Aldrich
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RBM3 siRNA (Human) - CRH4021 from Cohesion Biosciences
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RBM3 RNAi - H00005935-R02 from Novus Biologicals
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RBM3 - MBS8220529 from MyBioSource
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RBM3 CRISPR/Cas9 KO Plasmid (h2) - sc-406296-KO-2 from Santa Cruz Biotechnology
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RBM3 HDR Plasmid (h2) - sc-406296-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human RBM3 (NM_006743.4) - SHH390700 from Creative biogene
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Human RBM3 siRNA - orb264523 from Biorbyt
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RBM3 shRNA Plasmid (Human) - CHH4021 from Cohesion Biosciences
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