Gene Symbol | LYRM4 |
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Entrez Gene | 57128 |
Alt Symbol | C6orf149, CGI-203, COXPD19, ISD11 |
Species | Human |
Gene Type | protein-coding |
Description | LYR motif containing 4 |
Other Description | LYR motif-containing protein 4|homolog of yeast Isd11|mitochondrial matrix Nfs1 interacting protein |
Swissprots | A8K543 Q5XKP1 Q9HD34 |
Accessions | EAW55176 EAW55177 EAW55178 Q9HD34 AA764791 AF088060 AF170070 AAF25797 AF258559 AAG23762 AF285118 AAG01155 AK126470 AK291158 BAF83847 AK309458 AK309661 BC009552 AAH09552 BC067762 BC105601 BI226933 BI753819 BI758258 BM984752 BX353584 BX446965 CA310019 CK819966 EU831799 ACE87317 EU831876 ACE86635 HG498947 HY168919 XM_005249237 XP_005249294 XM_005249239 XP_005249296 XM_006715151 XP_006715214 XM_011514758 XP_011513060 NM_001164840 NP_001158312 NM_001164841 NP_001158313 NM_020408 NP_065141 NR_104417 NR_104418 |
Function | Required for nuclear and mitochondrial iron-sulfur protein biosynthesis. {ECO:0000269|PubMed:17331979, ECO:0000269|PubMed:19454487}. |
Subcellular Location | Mitochondrion. Nucleus. |
Tissue Specificity | Reduced mRNA levels in Friedreich ataxia patients. {ECO:0000269|PubMed:17331979}. |
LYRM4 CRISPR/Cas9 KO Plasmid (h) - sc-412759 from Santa Cruz Biotechnology
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LYRM4 HDR Plasmid (h) - sc-412759-HDR from Santa Cruz Biotechnology
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LYRM4 Double Nickase Plasmid (h) - sc-412759-NIC from Santa Cruz Biotechnology
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LYRM4 Double Nickase Plasmid (h2) - sc-412759-NIC-2 from Santa Cruz Biotechnology
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LYRM4 CRISPR Activation Plasmid (h) - sc-412759-ACT from Santa Cruz Biotechnology
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LYRM4 CRISPR Activation Plasmid (h2) - sc-412759-ACT-2 from Santa Cruz Biotechnology
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LYRM4 Lentiviral Activation Particles (h) - sc-412759-LAC from Santa Cruz Biotechnology
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LYRM4 Lentiviral Activation Particles (h2) - sc-412759-LAC-2 from Santa Cruz Biotechnology
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LYRM4 siRNA (h) - sc-95519 from Santa Cruz Biotechnology
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LYRM4 shRNA Plasmid (h) - sc-95519-SH from Santa Cruz Biotechnology
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LYRM4 shRNA (h) Lentiviral Particles - sc-95519-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU222491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12866 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12866 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07915 from Sigma-Aldrich
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LYRM4 siRNA (Human) - CRJ1343 from Cohesion Biosciences
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shRNA set against Human LYRM4 (NM_020408.4) - SHH336159 from Creative biogene
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LYRM4 shRNA Plasmid (Human) - CHJ1343 from Cohesion Biosciences
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LYRM4 miRNA 3'UTR clone - MiUTR3H-12832 from Creative biogene
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LYRM4 miRNA 3'UTR clone - MiUTR3H-12833 from Creative biogene
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LYRM4 miRNA 3'UTR clone - MiUTR3H-12834 from Creative biogene
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