| Gene Symbol |
PCOLCE2
|
| Entrez Gene |
26577
|
| Alt Symbol |
PCPE2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
procollagen C-endopeptidase enhancer 2
|
| Other Description |
procollagen C-proteinase enhancer 2|procollagen COOH-terminal proteinase enhancer 2
|
| Swissprots |
D3DNG4 B2RCH9 Q9BRH3 Q9UKZ9
|
| Accessions |
CCQ43420 EAW78961 EAW78962 Q9UKZ9 AF098269 AAF04621 AK075478 BAG52150 AK223633 BAD97353 AK315121 BAG37576 AY035400 AAK63128 AY358557 AAQ88921 BC006265 BC152796 AAI52797 CD366192 CR536570 CAG38807 DA555576 DQ173439 DQ173440 DQ173443 DQ173444 DQ173446 DQ173447 DQ173448 DQ173450 DQ173451 DQ173452 DQ173454 DQ173455 DQ173456 DQ173457 DQ173458 DQ173460 DQ173461 DQ173462 DQ173463 DQ173464 DQ173465 DQ173466 DQ173467 DQ173468 DQ173470 DQ173471 DQ173473 DQ173474 DQ173476 DQ173477 DQ173478 DQ173479 DQ173480 DQ173481 DQ173483 DQ173484 DQ173485 DQ173486 DQ173487 DQ173488 DQ173489 DQ173490 DQ173491 DQ173492 NM_013363 NP_037495
|
| Function |
Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1. {ECO:0000269|PubMed:12393877}.
|
| Subcellular Location |
Secreted {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in the heart, trabecular meshwork, pituitary gland, bladder, mammary gland, trachea and placenta and weakly expressed in the brain. Expressed in cartilage. {ECO:0000269|PubMed:10873381, ECO:0000269|PubMed:11597177, ECO:0000269|PubMed:12393877}.
|
![Western Blot: PCOLE2 Overexpression Lysate (Adult Normal) [NBP2-10344] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PCOLE2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2743_PCOLE2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10344-img0001.jpg)