Gene Symbol |
pho2A
|
Entrez Gene |
8627596
|
Alt Symbol |
DDBDRAFT_0188828, DDBDRAFT_0191299, DDB_0188828, DDB_0191299
|
Species |
Dictyostelium discoideum
|
Gene Type |
protein-coding
|
Description |
protein phosphatase 2A catalytic subunit
|
Other Description |
protein phosphatase 2A subunit C
|
Swissprots |
Q54G92 Q9XZE5
|
Accessions |
EAL62258 XM_630699 XP_635791
|
Function |
Plays a role in activating the myosin contractile function. Dephosphorylates threonine at 'Thr-1823', 'Thr-1833' and 'Thr-2029' in the C-terminal tail region of myosin II heavy chain (mhcA). Drives the assembly of dephosphorylated myosin II filaments to allow myosin recruitment into the cytoskeleton. {ECO:0000269|PubMed:10491107}.
|
Subcellular Location |
Cytoplasm, cytosol. Nucleus speckle.
|
Top Pathways |
mRNA surveillance pathway
|