Gene Symbol | POLA2 |
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Entrez Gene | 23649 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | polymerase (DNA directed), alpha 2, accessory subunit |
Other Description | DNA polymerase alpha 70 kDa subunit|DNA polymerase alpha subunit B|polymerase (DNA directed), alpha 2 (70kD subunit)|polymerase (DNA-directed), alpha (70kD) |
Swissprots | B4DNB4 Q14181 Q9BPV3 |
Accessions | EAW74373 Q14181 AK025315 AK094569 BAG52888 AK297842 BAG60176 AK307831 AK309284 BC001347 AAH01347 BC002990 AAH02990 BC018813 BC018814 CR456737 CAG33018 DB045992 DQ892023 ABM82949 DQ895215 ABM86141 L24559 AAA16459 XM_011544877 XP_011543179 XM_011544878 XP_011543180 XM_011544879 XP_011543181 XM_011544880 XP_011543182 XM_011544881 XP_011543183 NM_002689 NP_002680 |
Function | May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. {ECO:0000250}. |
Subcellular Location | Nucleus. |
Top Pathways | DNA replication, Purine metabolism, Pyrimidine metabolism |
POLA2 CRISPR/Cas9 KO Plasmid (h) - sc-407688 from Santa Cruz Biotechnology
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POLA2 HDR Plasmid (h) - sc-407688-HDR from Santa Cruz Biotechnology
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POLA2 Double Nickase Plasmid (h) - sc-407688-NIC from Santa Cruz Biotechnology
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POLA2 Double Nickase Plasmid (h2) - sc-407688-NIC-2 from Santa Cruz Biotechnology
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POLA2 CRISPR Activation Plasmid (h) - sc-407688-ACT from Santa Cruz Biotechnology
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POLA2 CRISPR Activation Plasmid (h2) - sc-407688-ACT-2 from Santa Cruz Biotechnology
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POLA2 Lentiviral Activation Particles (h) - sc-407688-LAC from Santa Cruz Biotechnology
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POLA2 Lentiviral Activation Particles (h2) - sc-407688-LAC-2 from Santa Cruz Biotechnology
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POLA2 siRNA (h) - sc-96906 from Santa Cruz Biotechnology
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POLA2 shRNA Plasmid (h) - sc-96906-SH from Santa Cruz Biotechnology
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POLA2 shRNA (h) Lentiviral Particles - sc-96906-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU042241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17087 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17087 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03606 from Sigma-Aldrich
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POLA2 siRNA (Human) - CRH8423 from Cohesion Biosciences
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POLA2 RNAi - H00023649-R01 from Novus Biologicals
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shRNA set against Human POLA2 (NM_002689.2) - SHH379071 from Creative biogene
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shRNA set against Human POLA2(NM_002689.2) - SHR126112 from Creative biogene
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Human POLA2 siRNA - orb268925 from Biorbyt
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POLA2 shRNA Plasmid (Human) - CHH8423 from Cohesion Biosciences
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POLA2 miRNA 3'UTR clone - MiUTR1H-08061 from Creative biogene
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