STAT6

Gene Symbol STAT6
Entrez Gene 6778
Alt Symbol D12S1644, IL-4-STAT, STAT6B, STAT6C
Species Human
Gene Type protein-coding
Description signal transducer and activator of transcription 6, interleukin-4 induced
Other Description STAT, interleukin4-induced|signal transducer and activator of transcription 6|transcription factor IL-4 STAT
Swissprots F5GXI9 P42226 Q5FBW5 B7ZA27 Q71UP4 A8K316
Accessions AAC51204 AAC67525 AAL06595 CAD22978 P42226 AB103088 BAD89431 AB103089 BAD89432 AI082533 AK290431 BAF83120 AK291044 BAF83733 AK298721 BAG60875 AK299094 BAG61154 AK308751 AK312471 BAG35377 AK316142 BAH14513 AK316236 BAH14607 AY615283 AAU04439 BC004973 BC005823 BC075852 AAH75852 BQ028928 BT007380 AAP36044 U16031 AAA57193 XM_006719574 XP_006719637 XM_006719575 XP_006719638 XM_011538703 XP_011537005 XM_011538704 XP_011537006 XM_011538705 XP_011537007 XM_011538706 XP_011537008 XM_011538707 XP_011537009 XM_011538708 XP_011537010 XM_011538709 XP_011537011 NM_001178078 NP_001171549 NM_001178079 NP_001171550 NM_001178080 NP_001171551 NM_001178081 NP_001171552 NM_003153 NP_003144 NR_033659
Function Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. {ECO:0000269|PubMed:17210636}.
Subcellular Location Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Top Pathways Jak-STAT signaling pathway, Inflammatory bowel disease (IBD)

Phospho-Stat6 (Tyr641) Antibody - 9361 from Cell Signaling Technology

Prices $109.00, $287.00, $678.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots), 300 µl (30 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Daudi cells, treated with IL-4 (100 ng/ml) for the indicated times using Phospho-Stat6 (Tyr641) Antibody (upper) or Stat6 antibody (lower).

Phospho-Stat6 (Tyr641) (C11A12) Rabbit mAb - 9364 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C11A12
Western blot analysis of extracts from HeLa and ACHN cells, untreated or treated with IL-4 (15 min), using Phospho-Stat6 (Tyr641) (C11A12) Rabbit mAb (upper) or Stat6 Antibody #9362 (lower).

Stat6 Antibody - 9362 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines, using Stat6 Antibody.

Stat6 (D3H4) Rabbit mAb - 5397 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3H4
Western blot analysis of extracts from various cell lines using Stat6 (D3H4) Rabbit mAb.

Phospho-Stat6 (Tyr641) (5A4) Mouse mAb - 9366 from Cell Signaling Technology

Host Mouse
Clonality Monoclonal
Clone 5A4

Phospho-Stat6 (Tyr641) (5A4) Mouse mAb - 5200 from Cell Signaling Technology

Host Mouse
Clonality Monoclonal
Clone 5A4

Stat6 (D-1) - sc-374021 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat6 (D-1): sc-374021. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

Stat6 (E-10) - sc-271213 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat6 (E-10): sc-271213. Western blot analysis of Stat6 expression in non-transfected 293T: sc-117752 (A), human Stat6 transfected 293T: sc-117401 (B) and BJAB (C) whole cell lysates.

Stat6 (M-20) - sc-981 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Stat6 (M-20)-G: sc-981-G. Western blot analysis of Stat6 expression in NIH/3T3 whole cell lysate.

Stat6 (M-200) - sc-1698 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Stat6 (M-200): sc-1698. Western blot analysis of Stat6 expression in NIH/3T3 (A), KNRK (B) and RAW 264.7 (C) whole cell lysates.

Stat6 (AS6-45.13.9) - sc-53611 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Hamster
Clonality Monoclonal
Stat6 (AS6-45.13.9): sc-53611. Western blot analysis of Stat6 expression in K-562 (A), HeLa (B) and Jurkat (C) nuclear extracts.

Stat6 (C-9) - sc-1689 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Stat6 (C-9): sc-1689. Western blot analysis of Stat6 expression in NIH/3T3 (A) and KNRK (B) whole cell lysates.

Stat6 (AS6-10.1.1) - sc-53610 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Hamster
Clonality Monoclonal
Stat6 (AS6-10.1.1): sc-53610. Western blot analysis of Stat6 expression in HeLa whole cell lysate.

Stat6 (S-20) - sc-621 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Stat6 (S-20): sc-621. Western blot analysis of Stat6 expression in KNRK (A), RAW 264.7 (B), BJAB (C) and Jurkat (D) whole cell lysates.

Stat6 (23) - sc-136236 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
Stat6 (23): sc-136236. Immunofluorescence staining of HeLa cells showing nuclear and cytoplasmic localization.

Stat6 (8C12 ) - sc-81539 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
Stat6 (8C12 ): sc-81539. Western blot analysis of Stat6 expression in non-transfected: sc-117752 (A) and human Stat6 transfected: sc-117401 (B) 293T whole cell lysates.

p-Stat6 (Tyr 641) - sc-11762 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

p-Stat6 (Tyr 641) - sc-101808 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-Stat6 (Tyr 641): sc-101808. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear staining.

p-Stat6 (Thr 645) - sc-101807 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
p-Stat6 (Thr 645): sc-101807. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human breast carcinoma tissue showing nuclear staining.

p-Stat6 (16E12) - sc-81525 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
p-Stat6 (16E12): sc-81525. Western blot analysis of Stat6 phosphorylation in untreated (A) and IL4-treated (B) Hep G2 whole cell lysates.

p-Stat6 (pY641.18) - sc-136019 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
p-Stat6 (pY641.18): sc-136019. Western blot analysis of Stat6 phosphorylation in untreated (A) or IL-4-treated (B) human endothelial cells.

Anti-STAT6 (phospho T645) antibody - ab30650 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab30650 staining human STAT6 in breast carcinoma by Immunohistochemistry, Paraffin embedded tissue. Left image antibody un-treated. Right image antibody pre-incubated with synthetic phosphopeptide.

Anti-STAT6 (phospho T645) antibody - ab195701 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-STAT6 (phospho T645) antibody (ab195701) at 1/500 dilutionLane 1 : Whole lysate of HeLa cells treated with IL4 with antigen-specific peptideLane 2 : Whole lysate of HeLa cells treated with IL4Lysates/proteins at 12.5 µg per lane.

Anti-STAT6 (phospho T645) antibody - ab119326 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab119326 at 1/50 dilution staining STAT6 in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-STAT6 (phospho Y641) antibody - ab28829 from Abcam

Prices $387.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of breast carcinom using ab28829 preincubated with synthesised phospho-peptide.
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