Gene Symbol | SLC9B2 |
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Entrez Gene | 133308 |
Alt Symbol | NHA2, NHE10, NHEDC2 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 |
Other Description | NHE domain-containing protein 2|Na(+)/H(+) exchanger-like domain-containing protein 2|Na+/H+ exchanger domain containing 2|mitochondrial Na(+)/H(+) exchanger NHA2|mitochondrial sodium/hydrogen exchanger 9B2|mitochondrial sodium/hydrogen exchanger NHA2|sodium/hydrogen exchanger-like domain-containing protein 2|solute carrier family 9 subfamily B member 2|solute carrier family 9, subfamily B (cation proton antiporter 2), member 2 |
Swissprots | B5ME52 Q96D95 Q86UD5 Q6ZMD8 |
Accessions | EAX06159 EAX06160 EAX06161 Q86UD5 AA233228 AK172823 BAD18790 AK297010 BAH12474 AK298506 BAH12802 AK299888 BAH13162 BC009732 AAH09732 BC047447 AAH47447 BI914487 BI962996 BM683318 BX359760 CA447309 DC297189 XM_005262758 XP_005262815 XM_006714085 XP_006714148 XM_006714086 XP_006714149 XM_006714088 XP_006714151 XR_427529 NM_001300754 NP_001287683 NM_001300756 NP_001287685 NM_178833 NP_849155 |
Function | Electroneutral exchange of protons for Na(+) and Li(+) across the inner mitochondrial membrane. Contributes to the organellar volume homeostasis. Required for osteoclast differentiation and bone resorption activity (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. |
Tissue Specificity | Detected in red blood cells (at protein level). |
NHEDC2 CRISPR/Cas9 KO Plasmid (h) - sc-414401 from Santa Cruz Biotechnology
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NHEDC2 HDR Plasmid (h) - sc-414401-HDR from Santa Cruz Biotechnology
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NHEDC2 Double Nickase Plasmid (h) - sc-414401-NIC from Santa Cruz Biotechnology
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NHEDC2 Double Nickase Plasmid (h2) - sc-414401-NIC-2 from Santa Cruz Biotechnology
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NHEDC2 CRISPR Activation Plasmid (h) - sc-414401-ACT from Santa Cruz Biotechnology
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NHEDC2 CRISPR Activation Plasmid (h2) - sc-414401-ACT-2 from Santa Cruz Biotechnology
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NHEDC2 Lentiviral Activation Particles (h) - sc-414401-LAC from Santa Cruz Biotechnology
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NHEDC2 Lentiviral Activation Particles (h2) - sc-414401-LAC-2 from Santa Cruz Biotechnology
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NHEDC2 siRNA (h) - sc-88995 from Santa Cruz Biotechnology
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NHEDC2 shRNA Plasmid (h) - sc-88995-SH from Santa Cruz Biotechnology
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NHEDC2 shRNA (h) Lentiviral Particles - sc-88995-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU098231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15277 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15277 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00367 from Sigma-Aldrich
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SLC9B2 siRNA (Human) - CRJ5112 from Cohesion Biosciences
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NHA2/SLC9B2/NHEDC2 RNAi - H00133308-R01 from Novus Biologicals
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SLC9B2 - MBS8234927 from MyBioSource
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shRNA set against Human NHEDC2 (NM_178833.4) - SHH352192 from Creative biogene
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Human SLC9B2 siRNA - orb275613 from Biorbyt
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SLC9B2 shRNA Plasmid (Human) - CHJ5112 from Cohesion Biosciences
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SLC9B2 miRNA 3'UTR clone - MiUTR3H-12102 from Creative biogene
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