Gene Symbol |
SAR1A
|
Entrez Gene |
56681
|
Alt Symbol |
SAR1, SARA1, Sara, masra2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
secretion associated, Ras related GTPase 1A
|
Other Description |
COPII-associated small GTPase|GTP-binding protein SAR1a|SAR1 gene homolog A|SAR1 homolog A|SAR1a gene homolog 1
|
Swissprots |
B4DQ19 Q9NR31
|
Accessions |
CAH25921 EAW54378 EAW54379 EAW54380 EAW54381 Q9NR31 AF086166 AF087897 AAP97196 AF217959 AAQ13891 AF261717 AAF81741 AF274026 AAM69363 AF318066 AAL27183 AK025857 AK298591 BAG60781 AK312469 BAG35376 AL136724 CAB66658 AW128933 AY008268 AAG16638 BC003658 AAH03658 BG327663 CR533492 CAG38523 DB216796 DQ587286 DR763562 EB388518 EU831972 ACE87413 EU832065 ACE86727 HQ448692 ADQ33170 NM_001142648 NP_001136120 NM_020150 NP_064535
|
Function |
Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). {ECO:0000250, ECO:0000269|PubMed:17005010}.
|
Subcellular Location |
Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}.
|
Top Pathways |
Protein processing in endoplasmic reticulum, Legionellosis
|