| Gene Symbol |
ZFAND6
|
| Entrez Gene |
54469
|
| Alt Symbol |
AWP1, ZA20D3, ZFAND5B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger, AN1-type domain 6
|
| Other Description |
AN1-type zinc finger protein 6|protein associated with PRK1|zinc finger, A20 domain containing 3
|
| Swissprots |
Q9GZY3 D3DW92 D3DW94 O95792 Q6FIF0 Q9BQF7
|
| Accessions |
EAW99122 EAW99123 EAW99124 EAW99125 EAW99126 EAW99127 Q6FIF0 AF061739 AAD17528 AF261138 AAG44674 AJ251095 CAC14876 AK055881 AK312646 BAG35530 AL136598 CAB66533 AW571396 BC005283 AAH05283 BG720174 BI562073 BP231220 BP234517 BX363429 CN428457 CR533476 CAG38507 DA091136 DB050060 DR762914 EU446810 ABZ92339 EU832283 ACE87540 EU832368 ACE86853 XM_011521683 XP_011519985 XM_011521684 XP_011519986 NM_001242911 NP_001229840 NM_001242912 NP_001229841 NM_001242913 NP_001229842 NM_001242914 NP_001229843 NM_001242915 NP_001229844 NM_001242916 NP_001229845 NM_001242917 NP_001229846 NM_001242918 NP_001229847 NM_001242919 NP_001229848 NM_019006 NP_061879
|
| Function |
Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'- linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed with high level in heart, skeletal muscle, liver, kidney and placenta. {ECO:0000269|PubMed:11054541}.
|
![Western Blot: ZA20D3 Overexpression Lysate (Adult Normal) [NBL1-18015] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ZA20D3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7740_ZA20D3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-18015-img0002.jpg)