| Gene Symbol |
URM1
|
| Entrez Gene |
100275675
|
| Alt Symbol |
-
|
| Species |
Corn
|
| Gene Type |
protein-coding
|
| Description |
Ubiquitin-related modifier 1 homolog
|
| Other Description |
GRMZM2G179689|ubiquitin modifier 1-like protein|ubiquitin-related modifier 1 homolog
|
| Swissprots |
B6SXH2
|
| Accessions |
B6SXH2 DAA62542 EU957437 ACG29555 XM_008652962 XP_008651184 NM_001149704 NP_001143176
|
| Function |
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates. {ECO:0000255|HAMAP-Rule:MF_03048}.
|
| Subcellular Location |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03048}.
|
| Top Pathways |
Sulfur relay system
|