| Gene Symbol | SPCS1 |
|---|---|
| Entrez Gene | 28972 |
| Alt Symbol | HSPC033, SPC1, SPC12, YJR010C-A |
| Species | Human |
| Gene Type | protein-coding |
| Description | signal peptidase complex subunit 1 homolog (S. cerevisiae) |
| Other Description | SPase 12 kDa subunit|microsomal signal peptidase 12 kDa subunit|signal peptidase 12kDa|signal peptidase complex subunit 1 |
| Swissprots | Q9Y6A9 Q9BVW1 B3KNF8 |
| Accessions | EAW65257 Q9Y6A9 AF092138 AAD40380 AK027426 BAG51320 AX775783 CAE11591 AX775785 CAE11592 AX775787 CAE11593 AX775833 CAE11616 BC000884 AAH00884 BG724036 BI826431 BQ423345 BU070128 CA309210 DB459917 L38852 AAL31361 NM_014041 NP_054760 |
| Function | Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}. |
| Subcellular Location | Microsome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | Protein export |