Gene Symbol |
RBBP9
|
Entrez Gene |
10741
|
Alt Symbol |
BOG, RBBP10
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
retinoblastoma binding protein 9
|
Other Description |
B5T overexpressed gene protein|B5T-overexpressed gene protein|RBBP-10|RBBP-9|putative hydrolase RBBP9|retinoblastoma-binding protein 10|retinoblastoma-binding protein 9|retinoma-binding protein 9
|
Swissprots |
O75884 Q9H1D8 D3DW31 Q5JPH9
|
Accessions |
EAX10236 EAX10237 EAX10238 O75884 AF039564 AAC63498 AF237576 AAL83721 AK023897 AL832411 CAI46193 BC015938 AAH15938 BC020627 BC026880 EU446767 ABZ92296 XM_005260652 XP_005260709 NM_006606 NP_006597 NM_153328
|
Function |
May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta1 through interaction with retinoblastoma and the subsequent displacement of E2F-1.
|
Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12296629}. Nucleus {ECO:0000269|PubMed:12296629}.
|
Tissue Specificity |
Widely expressed. Expressed at higher levels in tumor tissues than in normal tissues.
|